Effects of cadmium on some haematological and biochemical characteristics of Oreochromis niloticus (Linnaeus, 1758) dietary supplemented with tomato paste and vitamin E.

Fish Physiology and Biochemistry
I MekkawyMervat Naguib

Abstract

The present study investigates the potential protective effects of tomato paste (9 mg/kg-lycopene) in comparison with vitamin E (50 mg/kg) against the impacts of cadmium (Cd) toxicity (4.64 mg/l: ¼ of 96 h LC50) on fishes Cd exposed for 15 and 30 days. Cd impacts were evaluated in terms of biological, haematological and biochemical characteristics. Cd significantly induced free radicals in serum and liver. The activities of aspartate aminotransferase and alanine aminotransferase in serum were significantly increased due to Cd. Treatment with Cd caused a significant increase in Lipid peroxidation and DNA fragmentation in liver tissue and serum glucose and total lipid. On the other hand, Cd significantly led to decline in serum total protein, blood haemoglobin, red blood cell count, haematocrit value, mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration. Dietary supplementation with vitamin E and/or tomato paste to Cd-exposed fish declined significantly the increased lipid peroxidation and DNA fragmentation in liver tissue and the increased aspartate aminotransferase, alanine aminotransferase, glucose and total lipid in serum to the normal condition. This supplementation also signif...Continue Reading

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Citations

Sep 15, 2012·Pakistan Journal of Biological Sciences : PJBS·Bothaina M KhidrAbdel Salam M I Ohaida
Apr 23, 2013·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Nicola Franchi, Loriano Ballarin
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Oct 1, 2020·Environmental Science and Pollution Research International·Saima NazRifat Ullah Khan
Jul 20, 2017·Fish Physiology and Biochemistry·Heba S Hamed, Alaa G M Osman
Mar 14, 2018·Environmental Science and Pollution Research International·Abeer A Alm-EldeenSalma Alzahaby
Feb 25, 2021·Bulletin of Environmental Contamination and Toxicology·Marwan A Ibrahim, Rehab M Mosaad
Sep 14, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Alaa El-Din H SayedHamdy A M Soliman

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