Effects of Calcium Plus Vitamin D Supplementation on Anthropometric Measurements and Blood Pressure in Vitamin D Insufficient People with Type 2 Diabetes: A Randomized Controlled Clinical Trial

Journal of the American College of Nutrition
Marjan TabeshAhmad Esmaillzadeh

Abstract

Up to 75% of the risk of type 2 diabetes is attributable to obesity. Therefore, finding a way to control obesity can be useful for management of diabetes. This study was performed to assess the effects of vitamin D3 and calcium supplementation on anthropometric measurements and blood pressure in vitamin D insufficient people with type 2 diabetes. One hundred eighteen patients with diabetes were enrolled in this randomized placebo-controlled clinical trial. All subjects were randomly assigned into 4 groups receiving (1) 50,000 IU/wk vitamin D3 plus (equal to 7143 IU/d) calcium placebo; (2) 1000 mg/d calcium plus vitamin D3 placebo; (3) 50,000 IU/wk vitamin D3 (equal to 7143 IU/d) plus 1000 mg/d calcium; or (4) vitamin D3 placebo plus calcium placebo for 8 weeks. Anthropometric measurements and blood pressure were assessed at study baseline and after 8 weeks of intervention. A greater reduction in body mass index was observed in calcium plus vitamin D group than other groups (p = 0.03). Comparison of changes in waist circumference among 4 groups revealed no significant difference in crude model (p = 0.21) and when the effect of confounders was taken into account (p = 0.08). Calcium supplementation resulted in a significant reduct...Continue Reading

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Citations

Oct 16, 2015·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·M SamimiA Esmaillzadeh
Sep 25, 2016·The Journal of Steroid Biochemistry and Molecular Biology·Sunil J Wimalawansa
Sep 25, 2016·The Journal of Steroid Biochemistry and Molecular Biology·Sunil J Wimalawansa
Jul 28, 2019·The Cochrane Database of Systematic Reviews·Cristina PalaciosJuan Pablo Peña-Rosas
Apr 11, 2020·Journal of the American College of Nutrition·Virginia M LindleySushil K Jain

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Clinical Trials Mentioned

NCT01662193

Software Mentioned

Statistical Package for Social Science
Nutritionist IV

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