Effects of cannabinoid CB1 receptor antagonist rimonabant in consolidation and reconsolidation of methamphetamine reward memory in mice.

Psychopharmacology
Lu-lu YuLin Lu

Abstract

Previous studies have shown that cannabinoid CB1 receptors play an important role in specific aspects of learning and memory, yet there has been no systematic study focusing on the involvement of cannabinoid CB1 receptors in methamphetamine-related reward memory. The purpose of this study was to examine whether rimonabant, a cannabinoid CB1 receptor antagonist, would disrupt the consolidation and reconsolidation of methamphetamine-related reward memory, using conditioned place preference paradigm (CPP). Separate groups of male Kunming mice were trained to acquire methamphetamine CPP. Vehicle or rimonabant (1 mg/kg or 3 mg/kg, i.p.) was given at different time points: immediately after each CPP training session (consolidation), 30 min before the reactivation of CPP (retrieval), or immediately after the reactivation of CPP (reconsolidation). Methamphetamine CPP was retested 24 h and 1 and 2 weeks after rimonabant administration. Rimonabant at doses of 1 and 3 mg/kg significantly inhibited the consolidation of methamphetamine CPP. Only high-dose rimonabant (3 mg/kg) disrupted the retrieval and reconsolidation of methamphetamine CPP. Rimonabant had no effect on methamphetamine CPP in the absence of methamphetamine CPP reactivation....Continue Reading

References

Oct 1, 1990·Trends in Neurosciences·A C HowlettM Herkenham
Oct 1, 1994·Trends in Pharmacological Sciences·L Pulvirenti, G F Koob
Jun 15, 1999·Progress in Neurobiology·A Ameri
Jul 6, 2000·Journal of Physiology and Biochemistry·R Hernández-TristánM L Leret
Jan 4, 2001·Japanese Journal of Pharmacology·T Yamamoto, K Takada
Mar 23, 2001·Hippocampus·S G AnagnostarasM S Fanselow
Oct 3, 2001·The American Journal on Addictions·E J Nestler
Oct 9, 2001·Nature Medicine·T J De VriesA N Schoffelmeer
Dec 18, 2001·Neurocase·H J SpiersN Burgess
Apr 27, 2002·Science·Rachel I Wilson, Roger A Nicoll
Jul 4, 2002·Journal of Psychopharmacology·Jana VinklerováAlexandra Sulcová
Jan 22, 2003·Trends in Neurosciences·Karim Nader
Jan 23, 2003·Proceedings of the National Academy of Sciences of the United States of America·Lei WangGeorge Kunos
Oct 3, 2003·European Journal of Pharmacology·Mary C Wolff, J David Leander
Apr 16, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Kusnandar AnggadiredjaTsuneyuki Yamamoto
Sep 24, 2004·The European Journal of Neuroscience·Daniela ViganòTiziana Rubino
Oct 7, 2004·Neuropharmacology·Terry E Robinson, Bryan Kolb
Nov 5, 2004·The Journal of Pharmacology and Experimental Therapeutics·Bernard Le Foll, Steven R Goldberg
Nov 16, 2004·Annals of the New York Academy of Sciences·Basalingappa L Hungund, Balapal S Basavarajappa
Dec 8, 2004·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Gian Luigi GessaGiancarlo Colombo
May 3, 2005·Neuroscience Letters·Reinaldo Naoto TakahashiMarcelo Soares Fernandes
Jun 1, 2005·Pharmacology, Biochemistry, and Behavior·Jonathon C Arnold
Jun 7, 2005·Pharmacology, Biochemistry, and Behavior·Caroline CohenGuy Griebel
Jun 7, 2005·Pharmacology, Biochemistry, and Behavior·Eliot L Gardner
Jul 5, 2005·Trends in Pharmacological Sciences·Taco J De Vries, Anton N M Schoffelmeer
Aug 2, 2005·The American Journal of Psychiatry·Steven E Hyman
Aug 16, 2005·Nature·Glenda C HarrisGary Aston-Jones
Dec 27, 2005·Alcohol·Paola MaccioniGiancarlo Colombo
Jan 18, 2006·Acta Pharmacologica Sinica·Yu-xia FangLin Lu
Feb 14, 2006·Proceedings of the National Academy of Sciences of the United States of America·Emmanuel ValjentJean-Antoine Girault
Jun 17, 2006·Annual Review of Neuroscience·Steven E HymanEric J Nestler
Aug 15, 2006·Neurobiology of Learning and Memory·Yu-Min KuoLung Yu
Aug 18, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Zheng-Xiong XiEliot L Gardner
Aug 26, 2006·Neuroreport·Rick E BernardiStephen P Berger
Nov 7, 2006·Trends in Neurosciences·Lin LuYavin Shaham

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Citations

Jan 11, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Zhen-Yu RenLin Lu
Apr 19, 2012·Hybridoma·Xinglin KuangChongjie Zhang
Nov 20, 2013·Psychopharmacology·Cristiane Ribeiro De CarvalhoReinaldo Naoto Takahashi
Feb 3, 2016·Addiction Biology·Cristiane Ribeiro de Carvalho, Reinaldo Naoto Takahashi
Feb 22, 2012·Neuroscience and Biobehavioral Reviews·Barbara A Sorg
Feb 19, 2013·Current Opinion in Neurobiology·Natalie C Tronson, Jane R Taylor
Dec 28, 2010·Neuroscience·B A SorgH T Jansen
Jan 25, 2011·Pharmacology, Biochemistry, and Behavior·Hai-Shui ShiLin Lu
Apr 8, 2014·Industrial Health·Gil Soon ChoiEun-Kee Park
Nov 29, 2016·Frontiers in Cellular Neuroscience·Kari A Johnson, David M Lovinger
Sep 8, 2017·Journal of Psychopharmacology·Anna BrancatoCarla Cannizzaro
Nov 3, 2020·Frontiers in Behavioral Neuroscience·Greer McKendrick, Nicholas M Graziane
Aug 8, 2021·International Journal of Molecular Sciences·Yosef AvchalumovChitra D Mandyam
Aug 23, 2021·Psychoneuroendocrinology·Heng-Ai ChangSherry Shu-Jung Hu

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