Effects of cell phone radiation on lipid peroxidation, glutathione and nitric oxide levels in mouse brain during epileptic seizure

Journal of Chemical Neuroanatomy
Meric A EsmekayaNesrin Seyhan

Abstract

The objective of the this study was to evaluate the effects of cellular phone radiation on oxidative stress parameters and oxide levels in mouse brain during pentylenetetrazole (PTZ) induced epileptic seizure. Eight weeks old mice were used in the study. Animals were distributed in the following groups: Group I: Control group treated with PTZ, Group II: 15min cellular phone radiation+PTZ treatment+30min cellular phone radiation, Group III: 30min cellular phone radiation+PTZ treatment+30min cellular phone radiation. The RF radiation was produced by a 900MHz cellular phone. Lipid peroxidation, which is the indicator of oxidative stress was quantified by measuring the formation of thiobarbituric acid reactive substances (TBARS). The glutathione (GSH) levels were determined by the Ellman method. Tissue total nitric oxide (NOx) levels were obtained using the Griess assay. Lipid peroxidation and NOx levels of brain tissue increased significantly in group II and III compared to group I. On the contrary, GSH levels were significantly lower in group II and III than group I. However, no statistically significant alterations in any of the endpoints were noted between group II and Group III. Overall, the experimental findings demonstrated ...Continue Reading

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Citations

Jan 24, 2019·Electromagnetic Biology and Medicine·Mehmet Esref AlkisMehmet Zulkuf Akdag
Dec 9, 2017·Naunyn-Schmiedeberg's Archives of Pharmacology·Sehkar OktayAysen Yarat
May 1, 2021·International Journal of Molecular Sciences·David Schuermann, Meike Mevissen
Jun 29, 2021·Acta Neurologica Scandinavica·Ali A Asadi-PooyaAnahita Asadi-Pooya

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