Effects of cessation of smoking on serum lipids and high density lipoprotein-cholesterol
Abstract
This study examined the effect of cessation of smoking on serum lipid and lipoprotein levels. Twenty-six females who smoked a minimum of 20 cigarettes per day for the past 5 years served as volunteers. Twelve subjects abstained from smoking for a period of 60 days (ex-smokers). Six stopped smoking for 30 days then resumed smoking for an additional 30 days (re-smokers). Eight subjects continued to smoke for the entire 60 days (smokers). Additionally, 10 females who had never smoked served as non-smoking controls (non-smokers). Pre-cessation HDL-C levels for all smoker groups were 15-20% (P less than 0.05) below those of non-smokers. By day 30 of cessation HDL-C levels of ex-smokers and re-smokers significantly increased by 5.7 and 10.5 mg/dl, respectively, and were significantly higher than those of smokers. At day 60, HDL-C of ex-smokers increased another 6.8 mg/dl to 63.9 mg/dl while levels of re-smokers returned to pre-cessation levels (50.7 mg/dl). The findings of this study suggest that low levels of HDL-C associated with smoking in females do not appear to be cumulative and can be reversed in as little as 30 days.
References
Citations
Influence of worksite environmental tobacco smoke on serum lipoprotein profiles of female nonsmokers
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