Effects of chronic ethanol ingestion on mid-latency auditory evoked potentials depend on length of exposure

Alcohol
E A FloydH K Rucker

Abstract

We hypothesized that chronic ethanol ingestion is associated with modifications in components of mid-latency auditory evoked potentials (MAEPs). To test this, male Long Evans rats were administered 10% ethanol in drinking water as the sole fluid source for 3, 6, or 9 months. MAEPs were obtained and compared to age-matched control groups. MAEPs were obtained from additional rats after 4 weeks of abstinence. Data were obtained for varying frequencies (4, 8, 16, 24, 32 kHz) and intensities (65, 75, 85 dB SPL). Three months of ethanol exposure was associated with increased latencies and amplitudes of Na and Pa. MAEP components recovered and returned to control values after 4 weeks' abstinence following 3 months of EtOH exposure. Few significant differences were observed in the ethanol-treated or abstinent group after 6 months' exposure. However, 9 months of ethanol exposure revealed a significant increase in latencies and decrease in amplitudes of both Na and Pa components. After 4 weeks of abstinence, the Na and Pa component peak latencies appeared earlier than age-matched controls. The Na and Pa peak amplitudes were slightly greater than the ethanol-treated group; however, they did not recover to control values. These findings su...Continue Reading

References

Nov 1, 1978·Electroencephalography and Clinical Neurophysiology·K C SquiresA Starr
Jan 1, 1992·Neuropsychobiology·F CadaveiraM Sánchez-Turet
Mar 1, 1990·Electroencephalography and Clinical Neurophysiology·F DíazC Grau
Sep 1, 1990·Electroencephalography and Clinical Neurophysiology·J A LeeR F Berman
Nov 22, 1991·Brain Research·D S Barth, S Di
Jan 1, 1991·Psychopharmacology·C L Ehlers, R I Chaplin
Aug 1, 1991·Alcoholism, Clinical and Experimental Research·F CadaveiraM Sanchez-Turet
Mar 29, 1991·Brain Research·T McGeeT Nicol
Sep 1, 1986·Electroencephalography and Clinical Neurophysiology·M Scherg, D Von Cramon
Feb 1, 1987·Electroencephalography and Clinical Neurophysiology·B PorjeszB Kissin
May 1, 1988·Electroencephalography and Clinical Neurophysiology·M P DeiberF Mauguière
Feb 1, 1974·Electroencephalography and Clinical Neurophysiology·T W PictonR Galambos
Aug 1, 1982·Electroencephalography and Clinical Neurophysiology·M W Church, H L Williams
Jul 1, 1984·Electroencephalography and Clinical Neurophysiology·M W ChurchJ A Holloway
Jan 1, 1980·Acta Psychiatrica Scandinavica. Supplementum·H BegleiterM Tenner
Jan 1, 1981·Alcoholism, Clinical and Experimental Research·B Porjesz, H Begleiter
Mar 6, 1981·Science·H BegleiterC L Chou
Jun 1, 1994·Electroencephalography and Clinical Neurophysiology·F CadaveiraC Grau

❮ Previous
Next ❯

Citations

Apr 3, 2001·Neurophysiologie clinique = Clinical neurophysiology·S Rodríguez HolguínF Cadaveira
Mar 10, 2001·Alcoholism, Clinical and Experimental Research·C L RandallA K Thevos
Apr 29, 2004·Alcoholism, Clinical and Experimental Research·Theodora DukaFulton T Crews
Jun 9, 2012·Alcoholism, Clinical and Experimental Research·Natalie L CuzenGeorge Fein

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.