PMID: 9649966Jul 3, 1998Paper

Effects of chronic opioid dependence and HIV-1 infection on pattern shift visual evoked potentials

Drug and Alcohol Dependence
L Bauer

Abstract

The goal of the present study was to examine the effects of opioid dependence, alone and in combination with asymptomatic HIV-1 infection, on the pattern shift visual evoked potential (PSVEP). For this purpose, three groups of patients were evaluated, including patients characterized by: (1) a past history (2-4 months abstinent) of DSM-IIIR opioid dependence (i.e. in partial remission); (2) a recent history (7 days abstinent) of opioid dependence with ongoing methadone maintenance; and (3) a recent history of opioid dependence, ongoing methadone maintenance, and asymptomatic HIV-1 infection. A group of healthy, non-drug dependent volunteers was also evaluated. Analyses revealed no PSVEP differences between patients with a past history of opioid dependence and healthy volunteers. There were also no PSVEP differences between methadone-maintained patients with or without HIV-1 infection. Collectively, however, the two methadone maintenance groups exhibited significant delays in the N75 and P100 components of the PSVEP relative to the other two groups. The delay in N75 latency was strongly correlated with self-reported years of heroin abuse, but not with years of cocaine, alcohol, or other drug abuse. These results are interpreted ...Continue Reading

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Citations

Dec 23, 2003·Progress in Neuro-psychopharmacology & Biological Psychiatry·Anna G Polunina, Dmitriy M Davydov
Mar 4, 2000·Peptides·A L VaccarinoA J Kastin
Jul 19, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·L O Bauer
Apr 22, 2015·Acta neurologica Belgica·Grace Y WangBruce R Russell
Dec 22, 2004·Progress in Neuro-psychopharmacology & Biological Psychiatry·Dmitry M Davydov, Anna G Polunina
Jun 4, 2015·Journal of Psychopharmacology·Grace Y WangBruce R Russell
Sep 3, 2020·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Sylvia FittingKurt F Hauser

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