Abstract
Cigarette smoking increased the risk of acute cardiac events related with endothelial dysfunction and increased sympathetic activity. Impaired autonomic nervous activity is recognized as a considerable symptom of cardiac dysfunction and is strongly associated with increased risk overall mortality. A total of 75 healthy habitual smokers (40 female, 35 male, mean age 36.5 +/- 8.5 years), and 73 non-smokers subjects (45 female, 28 male, mean age 34.6 +/- 7.2 years) were studied. LF and LF/HF ratio were significantly higher in smokers than in non-smokers. On the contrary, SDNN, SDANN, RMSSD, and HF values were lower in smokers compared to those in non-smokers. Not the duration of smoking but the number of cigarettes smoked per day was correlated with the HRV parameters and NT-pro BNP. Furthermore, the average levels of NT-pro BNP were found to be positively correlated with LF, LF/HF and inversely correlated with SDNN, SDANN, RMSSD and HF. As a result, smoking impaires sympathovagal balance and decreases the heart rate variability in healthy subjects. And even a one cigarette smoking leads to overt sympathetic excitation. Furthermore, smoking results in an increase in NT-proBNP levels and the changes in adrenergic nervous system and...Continue Reading
References
Sep 9, 1976·The New England Journal of Medicine·P E CryerS D Shah
May 1, 1992·Journal of Hypertension·A GroppelliG Mancia
Aug 1, 1991·Circulation·A MallianiS Cerutti
Jan 1, 1990·The American Journal of Cardiology·J HayanoK Takata
Aug 1, 1986·Circulation Research·M PaganiE Piccaluga
Aug 1, 1988·Hypertension·G ParatiG Mancia
Jan 30, 1986·The New England Journal of Medicine·A P HallstromR Ray
Apr 1, 1986·Circulation·M D WinnifordL D Hillis
Dec 1, 1973·The American Journal of Cardiology·W J MandelA McCullen
Apr 1, 1974·American Heart Journal·P Hill, E L Wynder
May 1, 1971·Annals of Internal Medicine·W S AronowS N Rokaw
Apr 1, 1967·The American Journal of Physiology·R A Nadeau, T N James
Jul 1, 1994·Circulation·G GrassiG Mancia
Nov 1, 1993·Circulation·D S CelermajerJ E Deanfield
Feb 17, 1994·The New England Journal of Medicine·D J MoliternoL D Hillis
Aug 1, 1995·Journal of Molecular and Cellular Cardiology·C KrügerM Haass
Mar 6, 1998·Journal of Hypertension·M FaillaG Mancia
Jun 18, 1998·American Heart Journal·M YotsukuraK Ishikawa
Aug 26, 1998·Circulation·K NarkiewiczV K Somers
Feb 4, 1999·Hypertension·J MinamiH Matsuoka
Apr 13, 1999·Circulation·B L AbramsonJ S Floras
Aug 14, 1999·Arteriosclerosis, Thrombosis, and Vascular Biology·H V HuikuriM H Frick
Aug 24, 1999·Fundamental & Clinical Pharmacology·I RagueneauC Funck-Brentano
Sep 12, 2000·Circulation·J M DekkerE G Schouten
Apr 13, 2001·Journal of the American College of Cardiology·H P Brunner-La RoccaM D Esler
May 18, 2001·The American Journal of Cardiology·G A LoperaR J Myerburg
Feb 6, 2002·Circulation·Emily LubienAlan S Maisel
Jun 29, 2002·The American Journal of Cardiology·Kenneth C BilchickRonald D Berger
Nov 2, 2002·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Mahbubul AlamRolf Nordlander
Apr 23, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Hyung-Kwan KimYoung-Bae Park
Nov 9, 2005·Scandinavian Journal of Work, Environment & Health·Fumio KobayashiJunichiro Hayano
Dec 13, 2005·American Heart Journal·Edmundo ArteagaCharles Mady
Citations
May 30, 2009·European Journal of Applied Physiology·Eva Henje BlomMartin Ingvar
Oct 17, 2012·PloS One·Luc LorgisMarianne Zeller
Jan 22, 2014·Environmental Toxicology and Pharmacology·Paweł Gać, Małgorzata Sobieszczańska
Feb 28, 2014·Environmental Toxicology and Pharmacology·Paweł Gać, Małgorzata Sobieszczańska
Sep 22, 2012·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Patrick SmithVäinö Turjanmaa
Sep 13, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Habiba KapayaPamela V Loughna
Dec 12, 2012·Neurotoxicology·Beatriz ValeraEric Dewailly
Apr 7, 2015·Heart & Lung : the Journal of Critical Care·Mona A AbedDebra K Moser
Jan 11, 2011·Epilepsy & Behavior : E&B·Gulce Unal YildizNurhan Ilhan
Nov 22, 2011·International Journal of Cardiology·Petros C DinasAndreas D Flouris
Apr 21, 2009·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Therese A KearyPatrick A Palmieri
May 31, 2011·Yonsei Medical Journal·Ki Chang NamDeok Won Kim
May 14, 2016·International Heart Journal·Ma DufangLi Xiao
Feb 13, 2016·Psychosomatic Medicine·Nancy L SinDavid M Almeida
Apr 30, 2016·British Journal of Clinical Pharmacology·Shuang LiangMark N Kirstein
Nov 12, 2016·Preventive Medicine·Mandy Xian HuBrenda W J H Penninx
Dec 25, 2015·European Journal of Preventive Cardiology·Stefanie AeschbacherDavid Conen
May 21, 2015·Einstein·Renata Melo GondimRaphael Mendes Ritti-Dias
Oct 7, 2009·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Goksel CagirciRamazan Akdemir
Sep 12, 2009·Seminars in Dialysis·Francesco LocatelliSalvatore Di Filippo
Feb 2, 2019·American Journal of Physiology. Heart and Circulatory Physiology·Daniel J ConklinAruni Bhatnagar
Jun 2, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Emmanuel H DuringM J de Leon
May 23, 2012·Seminars in Dialysis·Angela Yee-Moon Wang
Jul 22, 2017·Psychosomatic Medicine·Fernando BodinRichard P Sloan
Apr 10, 2019·PloS One·Federico MurgiaCristian Pattaro
Oct 17, 2020·Journal of the American Heart Association·Simin MahinradFarzaneh A Sorond