Effects of composite antimicrobial peptide on growth performance and health in weaned piglets

Animal Science Journal = Nihon Chikusan Gakkaihō
Jiankai ShiShengyu Xu

Abstract

This study was conducted to evaluate the effects of composite antimicrobial peptide (CAP) on growth performance and health status in weaned piglets. Over 28 days, 36 weaned piglets (body weight, 10.58 ± 0.99 kg) underwent three treatments: negative control (NC, basal diet), positive control (PC, basal diet + 20 mg/kg colistin sulphate + 50 mg/kg kitasamycin), and CAP treatment (CAP, basal diet with 400 mg/kg CAP). Average daily gain of piglets fed the CAP diet was greater (P < 0.05) than that of piglets fed the PC or NC diet during days 1-7, 8-14 and 15-21. Diarrhea rates of piglets fed the CAP or PC diet were lower (P < 0.05) than those of NC-fed piglets during days 1-7. Apparent total tract digestibility for dry matter and crude ash in CAP-fed piglets was greater (P < 0.05) than that of NC-fed piglets. In the CAP group, Lactobacillus and Bifidobacterium counts were greater (P < 0.05) and Escherichia coli counts were lower (P < 0.05) than numbers for the NC group. Our results indicate that dietary CAP had beneficial effects on growth performance and health status in weaned piglets.

References

Aug 1, 1982·Journal of Animal Science·K W KelleyJ A Regnier
Feb 8, 1997·Lancet·R E Hancock
Mar 6, 1998·Trends in Biotechnology·R E Hancock, R Lehrer
Dec 28, 1999·Peptides·A GiacomettiG Scalise
Oct 26, 2000·Current Opinion in Microbiology·S Monroe, R Polk
Jun 9, 2001·International Journal of Antimicrobial Agents·S SchwarzT R Walsh
Nov 3, 2005·Nature Clinical Practice. Gastroenterology & Hepatology·Jan WehkampEduard F Stange
Dec 7, 2005·Proceedings of the National Academy of Sciences of the United States of America·Jan WehkampCharles L Bevins
Jun 15, 2010·The Journal of Antimicrobial Chemotherapy·Anders S AndersenKaren A Krogfelt
Nov 19, 2014·Journal of Animal Science·Z H RenY Hu
May 7, 2016·International Journal of Molecular Sciences·Shuai WangShiyan Qiao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.