Sep 20, 2006

Effects of compression depth and pre-shock pauses predict defibrillation failure during cardiac arrest

Resuscitation
Dana P EdelsonLance B Becker

Abstract

Cardiopulmonary resuscitation (CPR) and electrical defibrillation are the primary treatment options for ventricular fibrillation (VF). While recent studies have shown that providing CPR prior to defibrillation may improve outcomes, the effects of CPR quality remain unclear. Specifically, the clinical effects of compression depth and pauses in chest compression prior to defibrillation (pre-shock pauses) are unknown. A prospective, multi-center, observational study of adult in-hospital and out-of-hospital cardiac resuscitations was conducted between March 2002 and December 2005. An investigational monitor/defibrillator equipped to measure compression characteristics during CPR was used. Data were analyzed from 60 consecutive resuscitations in which a first shock was administered for VF. The primary outcome was first shock success defined as removal of VF for at least 5s following defibrillation. A logistic regression analysis demonstrated that successful defibrillation was associated with shorter pre-shock pauses (adjusted odds ratio 1.86 for every 5s decrease; 95% confidence interval 1.10-3.15) and higher mean compression depth during the 30s of CPR preceding the pre-shock pause (adjusted odds ratio 1.99 for every 5mm increase; ...Continue Reading

  • References35
  • Citations349

References

  • References35
  • Citations349

Citations

Mentioned in this Paper

Acrocallosal Syndrome
Ventricular Fibrillation
Logistic Regression
Basic Cardiac Life Support
Shock
Blood Flow
GLI3 gene
Anterior Thoracic Region
Chest
Observation - Diagnostic Procedure

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