Effects of compression/stretching of the spermatic cord and blunt dissection on testicular growth and fertility

Journal of Pediatric Surgery
Seung-Eun ChoiWoo-Ki Kim

Abstract

This study was performed to investigate whether compression/stretching of the spermatic cord or blunt dissection influences testicular development and fertility. In addition, the authors evaluated whether the extents of testicular damage differ between these 2 surgical manipulations. Forty-four prepubertal male Sprague-Dawley (SD) rats (Harlan Sprague-Dawley Inc, Indianapolis, Ind) were divided into 3 groups: (1) the control group (CG) animals underwent a sham operation in the right groin, (2) the experimental group 1 (EG1) underwent compression/stretching of the right spermatic cord, and (3) the experimental group 2 (EG2) underwent dissection around the right spermatic cord structures. Testicular volumes, weights, mean seminiferous tubular diameters (MSTDs), mean testicular biopsy scores, and numbers of offspring and of pregnant females were evaluated. Right (operative) and left (nonoperative) testicular volumes were smaller in the EG2 group than in the CG or EG1 groups. Left MSTDs in the EG1 and EG2 groups increased more than in the CG group. Numbers of Sertoli cells in left testes differed in the 3 groups, in the order EG1 < CG < EG2. Mean testicular biopsy scores, offspring numbers, and pregnant female numbers were no diffe...Continue Reading

References

Nov 1, 1991·British Journal of Urology·D P Sandhu, D E Osborn
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May 1, 1988·Journal of Pediatric Surgery·F T SalmanE W Fonkalsrud
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Sep 10, 2008·Journal of Pediatric Surgery·Marcelo M SteganiSérgio O Ioshii

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Citations

May 30, 2014·International Urology and Nephrology·Reynaldo G GómezMiroslav Djordjevic
Jan 8, 2013·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·A Galbarriatu GutiérrezF Oliver Llinares
Aug 4, 2016·Acta Cirúrgica Brasileira·Salomão BrêtasCaroline Oliveira Brêtas
Aug 21, 2014·Acta Cirúrgica Brasileira·Salomão BrêtasJane Sant'Ana Castello

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