PMID: 6969119Dec 1, 1980Paper

Effects of cordycepin and cell dissociation on the synthesis of H1 histone by sea urchin embryos

Cell Differentiation
J W Brookbank

Abstract

A shift in the type of H1 histone synthesized during sea urchin development has been described previously. Early histone synthesis appears to be carried out using both newly transcribed mRNA and stored maternal message. The appearance of the later H1 molecule is reported to be under transcriptional control. The present report utilizes hybrid embryos and supports the idea of transcriptional control of the later histone, from mesenchyme blastula on. In addition, the inhibition of the switch from one H1 type to the other by cordycepin is described and discussed. Since one effect of cordycepin is the dissociation of the blastula into single cells, the effect of other means of dissociation was studied. No interference with the histone changeover was detected in cultures of dissociated embryonic cells.

References

Jan 1, 1978·Cold Spring Harbor Symposia on Quantitative Biology·K M NewrockL H Cohen
Jun 1, 1978·Cell Differentiation·J W Brookbank
Jan 1, 1979·Differentiation; Research in Biological Diversity·D P Easton, A H Whiteley
Aug 15, 1975·European Journal of Biochemistry·R A Laskey, A D Mills
Jan 1, 1976·Developmental Biology·R P Lifton, L H Kedes
Oct 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·A Skoultchi, P R Gross
Sep 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·K W GrossP R Gross
Apr 25, 1973·Journal of Molecular Biology·R L Seale, A I Aronson
Jan 4, 1974·Nature·J V RudermanP R Gross
Feb 1, 1974·Developmental Biology·J V Ruderman, P R Gross
Jul 1, 1974·European Journal of Biochemistry·W M Bonner, R A Laskey
Jun 28, 1972·Journal of Molecular Biology·M Adesnik, J E Darnell
Dec 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·S PenmanM Penman
Sep 17, 1970·Biochimica Et Biophysica Acta·L A Loeb, B Fansler
Apr 28, 1971·Journal of Molecular Biology·L C Benttinen, D G Comb
Mar 11, 1966·Science·M Spiegel, A Tyler
Sep 1, 1976·Developmental Biology·A A GineitisV I Vorob'ev
Jul 19, 2011·Neurobiology of Aging·Leonidas ChouliarasBart P F Rutten

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Citations

Oct 1, 1991·Developmental Biology·C Nocente-McGrathS G Ernst
Jan 1, 1984·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·J Pałyga
Jan 1, 1982·Differentiation; Research in Biological Diversity·J W Brookbank
Nov 1, 1982·The Journal of Experimental Zoology·M F Harrison, F H Wilt

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