Stereoscopic depth perception requires considerable neural computation, including the initial correspondence of the two retinal images, comparison across the local regions of the visual field and integration with other cues to depth. The most common cause for loss of stereoscopic vision is amblyopia, in which one eye has failed to form an adequate input to the visual cortex, usually due to strabismus (deviating eye) or anisometropia. However, the significant cortical processing required to produce the percept of depth means that, even when the retinal input is intact from both eyes, brain damage or dysfunction can interfere with stereoscopic vision. In this review, I examine the evidence for impairment of binocular vision and depth perception that can result from insults to the brain, including both discrete damage, temporal lobectomy and more systemic diseases such as posterior cortical atrophy.This article is part of the themed issue 'Vision in our three-dimensional world'.
Stereopsis after unilateral anterior temporal lobectomy. Dissociation between local and global measures
Stereoscopic depth discrimination in the visual cortex: neurons ideally suited as disparity detectors
Neuronal mechanisms underlying stereopsis: how do simple cells in the visual cortex encode binocular disparity?
Area V5 of the human brain: evidence from a combined study using positron emission tomography and magnetic resonance imaging
Atypical and typical presentations of Alzheimer's disease: a clinical, neuropsychological, neuroimaging and pathological study of 13 cases
Quantitative analysis of the responses of V1 neurons to horizontal disparity in dynamic random-dot stereograms
A network of occipito-temporal face-sensitive areas besides the right middle fusiform gyrus is necessary for normal face processing
Visual field maps, population receptive field sizes, and visual field coverage in the human MT+ complex
A causal role for V5/MT neurons coding motion-disparity conjunctions in resolving perceptual ambiguity
Perceptual relearning of binocular fusion after hypoxic brain damage: four controlled single-case treatment studies
Holmes and Horrax (1919) revisited: impaired binocular fusion as a cause of "flat vision" after right parietal brain damage - a case study
Cognitive functions and stereopsis in patients with Parkinson's disease and Alzheimer's disease using 3-dimensional television: a case controlled trial
Functional architecture for disparity in macaque inferior temporal cortex and its relationship to the architecture for faces, color, scenes, and visual field
The prevalence and diagnosis of 'stereoblindness' in adults less than 60 years of age: a best evidence synthesis
Fear of falling avoidance behavior affects the inter-relationship between vision impairment and diminished mobility in community-dwelling older adults
Microstructural properties of the vertical occipital fasciculus explain the variability in human stereoacuity
Ocular Manifestations of Alzheimer's and Other Neurodegenerative Diseases: The Prospect of the Eye as a Tool for the Early Diagnosis of Alzheimer's Disease
Age-Related Deficits in Binocular Vision Are Associated With Poorer Inhibitory Control in Healthy Older Adults
Brain Injury & Trauma
brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.