Effects of d-amphetamine, chlorpromazine, and chlordiazepoxide on intercurrent behavior during spaced-responding schedules

Journal of the Experimental Analysis of Behavior
J B Smith, F C Clark

Abstract

Effects of d-amphetamine, chlorpromazine, and chlordiazepoxide on lever pressing under direct control of spaced-responding schedules were compared with effects on intercurrent drinking and wheel running in the rat. Drug effects on lever pressing were systematically related to dose and were consistent for all animals; drug effects on intercurrent behavior were generally different for each animal. In the case of lever presses, increasing doses of d-amphetamine first increased and then decreased response rate, increasing doses of chlorpromazine produced graded decreases in response rate, and doses of chlordiazepoxide up to 40 mg/kg produced no effect on response rate. These data are discussed in context with the concept of schedule control, and it is suggested that the behavioral pharmacology of intercurrent behavior be explored as a useful procedure in the experimental analysis of intercurrent behavior.

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Citations

Dec 27, 2005·Behavioural Pharmacology·Angeles Pérez-Padilla, Ricardo Pellón
Nov 1, 1979·Journal of the Experimental Analysis of Behavior·D E McMillan
May 1, 1983·Journal of the Experimental Analysis of Behavior·K McIntireS Allard
May 25, 2011·Pharmacology, Biochemistry, and Behavior·N W GilpinM A Taffe

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