Effects of degrees of reaming on healing of segmental fractures in rats

Journal of Orthopaedic Trauma
S E UtvågO Reikerås

Abstract

To assess the effects of graded intramedullary reaming and nailing on the healing pattern of segmental diaphyseal fractures using male Wistar rats. In male Wistar rats we produced two standardized, partial osteotomies with an eight-millimeter intermediary fragment in the femoral diaphysis. The osteotomies were subsequently manually broken. In Group A, intramedullary reaming was performed to 1.6 millimeters, and the fracture was stabilized with a 1.6-millimeter steel pin. In Group B, the femoral canal was reamed to 2.0 millimeters, and a hollow steel tube of 2.0 millimeters was installed. The rats were allowed free movement. After four, eight, and twelve weeks, eight rats in each group were sacrificed and callus formation, biomechanical properties, and bone blood flow were evaluated. The callus area was relatively constant with time in Group B, whereas a reduction was observed in Group A at twelve weeks. The biomechanical properties increased throughout the experimental period in both groups, and no significant differences between the groups were detected in bending moment, bending rigidity, or fracture energy. Total bone blood flow was substantially increased at four weeks in both groups and decreased throughout the experimenta...Continue Reading

References

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Citations

Dec 3, 2008·The Journal of Bone and Joint Surgery. American Volume·UNKNOWN Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures InvestigatorsStephen D Walter
Oct 4, 2012·The Journal of Bone and Joint Surgery. American Volume·Emil H SchemitschUNKNOWN Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures (SPRINT) Investigators
Apr 20, 2010·The Orthopedic Clinics of North America·David L HelfetBeate Hanson
Feb 27, 2009·Injury·Yusuf OztürkmenMustafa Caniklioğlu
Oct 7, 2006·Biochemical and Biophysical Research Communications·C ColnotJ Helms
Nov 16, 2016·Nigerian Journal of Surgery : Official Publication of the Nigerian Surgical Research Society·Olasunkanmi M BabalolaAdebowale Adeniyi
Dec 19, 2012·The Open Orthopaedics Journal·M GriffinS Hindocha

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