Effects of diclofenac and salicylic acid exposure on Lemna minor: Is time a factor?

Environmental Research
G D AlkiminBruno Nunes

Abstract

The global occurrence of pharmaceuticals in the aquatic environment has been considered a particularly concerning problem with unknown consequences. Non-steroidal anti-inflammatory drugs (NSAIDs) including diclofenac (DCF) and salicylic acid (SA), are among the most frequently prescribed drugs in the world, being consequently commonly found in the aquatic environment. Prolonged experiments (with duration of exposure that surpass those recommended by already established testing guidelines) are important to obtain ecologically relevant data to address the issue of NSAIDs ecotoxicity, because by being more realistically (namely in terms of levels and durations of exposure), such tests may indicate realistic challenges posed to aquatic organisms. Among the most common test species that are used for assessing environmental quality, plants play a leading role. Lemna species are among the most important plants used for ecotoxicity testing. Therefore, the aim of this study was to evaluate the temporal effect of a prolonged exposure of DCF and SA on Lemna minor. To attain this purpose, L. minor plants were chronically exposed to 0, 4, 20, and 100 μg/L of both pharmaceuticals, and samplings were performed at 6, 10 and 14 days of exposure...Continue Reading

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Citations

Feb 2, 2020·The Science of the Total Environment·Rosa FreitasCaterina Faggio
Jun 26, 2020·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Gilberto Dias de AlkiminBruno Nunes
Jul 14, 2021·Journal of Separation Science·Alice M S RodriguesDidier Stien
Aug 28, 2021·International Journal of Molecular Sciences·Agnieszka SiemieniukMałgorzata Rudnicka

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