Effects of dietary aflatoxin on the health and performance of growing barrows

Journal of Animal Science
S M RustemeyerK M Cammack

Abstract

Aflatoxins, especially aflatoxin B1 (AFB1), can be greater in dried distillers grains with solubles (DDGS) because it can be concentrated during the ethanol production process. Increased use of DDGS in swine diets could potentially lead to an increased incidence of aflatoxicosis, a disease associated with decreased feed intake, reduced BW gain, and impaired liver function. The objective of this study was to determine the effects of AFB1 on the health, performance, and serum profile of growing barrows. Ninety Duroc × Yorkshire crossbred barrows were purchased (age = 35 ± 5 d; BW = 14.2 ± 3.0 kg), allocated to 9 pens with 10 pigs per pen, and randomly assigned to receive diets containing 0 µg/kg of AFB1 (CON), 250 µg/kg of AFB1 (LO), or 500 µg/kg of AFB1 (HI) for 7, 28, or 70 d in a 3 × 3 factorial arrangement of treatments. Feed intake was measured daily, and pigs were weighed and blood samples collected weekly. Serum was analyzed for concentrations of aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (BILI), and blood urea nitrogen (BUN). Both ADFI and ADG were negatively affected (P ≤ 0.001) by AFB1 treatment. Average daily feed intake was less (P < 0.05) in HI barrows than in CON barrows from w...Continue Reading

References

Oct 1, 1979·Journal of Animal Science·L L Southern, A J Clawson
Jan 1, 1993·Journal of Animal Science·M D LindemannG G Schurig
Sep 25, 2001·Toxicology·H S Hussein, J M Brasel
Mar 12, 2005·Diseases of Aquatic Organisms·Stein MortensenTristan Renault
Jul 7, 2005·Phytochemical Analysis : PCA·Jesús Gómez-CatalánJuan M Llobet
Oct 2, 2009·Journal of Agricultural and Food Chemistry·Yanhong ZhangGerald C Shurson

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Citations

Dec 17, 2016·Journal of Analytical Toxicology·Mayra C Di GregorioCarlos A F Oliveira
Apr 5, 2014·Chemistry : a European Journal·Akihiro Nomura, Christopher W Jones
Mar 19, 2011·Journal of Animal Science·S M RustemeyerK M Cammack
Mar 17, 2018·Fish Physiology and Biochemistry·Matheus D BaldisseraBernardo Baldisserotto
Mar 2, 2021·Frontiers in Veterinary Science·Lan ZhengSung Woo Kim

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