Effects of dietary chitosan on growth, lipid metabolism, immune response and antioxidant-related gene expression in Misgurnus anguillicaudatus

Beneficial Microbes
J YanJ Gao

Abstract

This study was performed to evaluate the effects of dietary chitosan supplementation on growth performance, lipid metabolism, gut microbial, antioxidant status and immune responses of juvenile loach (Misgurnus anguillicaudatus). Five experimental diets were formulated to contain graded levels of chitosan (0 (control), 0.5, 1, 2 and 5% CHI) for 50 days. Results of the present study showed that body weight gain was significantly higher in fish fed chitosan supplemented diets in dose dependent manner than control group. Increasing dietary chitosan levels reduced gut lipid content. Meanwhile the mRNA expression levels of intestine lipoprotein lipase and fatty acid binding protein 2 were significantly reduced with incremental dietary chitosan level. The percentages of total monounsaturated fatty acid decreased, while polyunsaturated fatty acid increased with dietary chitosan. The fish fed 0.5% CHI had higher mucus lysozyme activity (LZM) than those fed 0% CHI, but the LZM activity was significantly decreased with advancing chitosan supplement. The expression levels of superoxide dismutase, catalase and glutathione peroxidase revealed a similar trend, where the highest expressions were found in fish fed 5% CHI diet. In the term of in...Continue Reading

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Citations

Dec 31, 2019·Journal of Food and Drug Analysis·Yuting LiuJinglei Li
Feb 2, 2020·Environmental Science and Pollution Research International·Mohamed M Abdel-DaimSaad Alkahtani
May 28, 2020·Polymers·Yuanbing WuIsidoro Metón
Dec 22, 2019·Fish & Shellfish Immunology·Mahmoud A O DawoodMd Tawheed Hasan
Aug 8, 2021·Animals : an Open Access Journal From MDPI·Ana Gutiérrez FalcónJosé Luís Martín-Barrasa

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