Effects of different cycle regimens for frozen embryo transfer on perinatal outcomes of singletons.

Human Reproduction
Bian WangYun Wang

Abstract

Does the endometrial preparation protocol for frozen embryo transfer (FET) have an impact on perinatal outcomes? Singleton newborns from conceptions after an artificial FET cycle had a higher risk of being large for gestational age (LGA). Most previous studies have concentrated on the clinical pregnancy, miscarriage and live birth rates of different endometrial preparation protocols for FET. However, the impacts of these cycle regimens on perinatal outcomes including birthweight, gestational age (GA) and related outcomes require more investigation. We retrospectively analysed all singletons conceived by women who underwent non-donor FET cycles between July 2014 and July 2017. The propensity score matching (PSM) method using nearest neighbour matching at a proportion of 1:1 was established to adjust for factors that influence the probability of receiving different FET cycle regimens. The main outcomes of the study included birthweight and its related outcomes, Z-score, low birthweight (LBW, <2500 g), small for gestational age (SGA, ≤10th percentile of referential birthweight), LGA (≥90th percentile of referential birthweight) and macrosomia (birthweight >4000 g). The study outcomes also included GA at birth, preterm delivery (<3...Continue Reading

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Citations

Jan 2, 2021·Reproductive Biomedicine Online·Mathilde BourdonPietro Santulli
Apr 9, 2021·Journal of Assisted Reproduction and Genetics·Hanglin WuSongying Zhang
Jul 27, 2021·Frontiers in Endocrinology·Sezcan MumusogluHakan Yarali
Aug 27, 2021·American Journal of Obstetrics and Gynecology·Kirk P ConradValerie L Baker
Sep 28, 2021·Frontiers in Medicine·Freya WaschkiesFrauke von Versen-Höynck

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