Effects of different PEEP levels on respiratory mechanics and oxygenation after coronary artery bypass grafting

Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular
Daniel Lago BorgesJosimary Lima da Silva Lula

Abstract

To compare the effects of different levels of positive end-expiratory pressure on respiratory mechanics and oxygenation indexes in the immediate postoperative period of coronary artery bypass grafting. Randomized clinical trial in which 136 patients underwent coronary artery bypass grafting between January 2011 and March 2012 were divided into three groups and admitted to mechanical ventilation with different positive end-expiratory pressure levels: Group A, 5 cmH2O (n=44), Group B, 8 cmH2O (n=47) and Group C, 10 cmH2O (n=45). Data about respiratory mechanics were obtained from mechanical ventilator monitor and oxygenation indexes from arterial blood gas samples, collected twenty minutes after intensive care unit admission. Patients with chronic obstructive pulmonary disease and patients submitted to off-pump, emergency or combined operations were not included. For statistical analysis, we used Kruskal-Wallis, G and Chi-square tests, considering results significant when P<0.05. Groups were homogeneous in terms of demographic, clinical and surgical variables. Patients ventilated with positive end-expiratory pressure of 10 cmH2O (Group C) had best compliance (P=0.04) and airway resistance values, this, however, without statistica...Continue Reading

Associated Clinical Trials

Apr 28, 2017·Carlos Ferrando

Citations

Aug 25, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Zheng GuanXin Shen
Jul 16, 2016·Revista da Escola de Enfermagem da U S P·Camila Takao LopesAlba Lucia Bottura Leite de Barros
Dec 9, 2014·Current Opinion in Anaesthesiology·Carlos FerrandoFrancisco J Belda
May 12, 2015·Critical Care Medicine·R Scott Stephens, Glenn J R Whitman
May 10, 2018·Trials·Anna Geke AlgeraUNKNOWN RELAx Investigators and the PROVE Network Investigators
Jan 18, 2018·Archives of Physiotherapy·Vanessa Marques Ferreira MéndezIracema I K Umeda
Apr 19, 2015·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Camila T LopesAlba L Bottura Leite de Barros
Jul 17, 2021·Critical Care : the Official Journal of the Critical Care Forum·Tommaso PettenuzzoPaolo Navalesi

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