Effects of diode laser application on inflammation and mpo in periodontal tissues in a rat model

Journal of Applied Oral Science : Revista FOB
Mustafa Özay Usluİbrahim Hanifi Özercan

Abstract

In this study, we aimed to histologically and immunologically evaluate the effect of diode laser treatment when applied adjunctive to scaling and root planing (SRP) in an experimental periodontitis model. We used Wistar-Albino rats (n=60) with average weight of 230 g. Experimental periodontitis was induced by ligature at the right and left first mandibular molar teeth in all rats. After 11 days, the ligature was removed and rats were divided into two groups. The control group (n=30) received only SRP treatment, while the laser group (n=30) received a diode laser (GaAlAs, 810 nm, 1 W, 10 J, 20 s) treatment adjunctive to SRP. Ten rats in each group were sacrificed after 7, 15, and 30 days. Histopathological examination was performed in the left mandible of rats. Myeloperoxidase (MPO) was evaluated by western blot in the gingival specimens from the right mandible. MPO levels in the laser group were statistically significantly lower compared with the control group (p≤0.05). There was no statistically significance at any time between MPO levels in the control group (p>0.05). MPO levels in the laser group at the 7th day were statistically significantly higher compared to the 15th (p≤0.05) and the 30th day (p≤0.05). Inflammatory cell ...Continue Reading

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Citations

Nov 22, 2019·Photobiomodulation, Photomedicine, and Laser Surgery·Leila GholamiReza Fekrazad
Jun 26, 2020·Frontiers in Physiology·Beatriz Carmona FerreiraAna Cláudia Rossi
Mar 8, 2019·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Milena KosticJana Pesic Stankovic

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Methods Mentioned

BETA
electrophoreses
light microscopy

Software Mentioned

Power and Size
Olympus
Olympus DP Controller
Image Analyses System J
SPSS Statistics

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