Effects of drug residues in the faeces of cattle treated with injectable formulations of ivermectin and moxidectin on larvae of the bush fly, Musca vetustissima and the house fly, Musca domestica

Australian Veterinary Journal
K G WardhaughK Shelley

Abstract

To assess the toxicity of residues of ivermectin and moxidectin in cattle faeces collected at intervals after treatment. Replicated bioassays of faeces using larvae of the bush fly, Musca vetustissima and the house fly, Musca domestica. Two groups of five Murray Grey x Aberdeen Angus steers were treated with injectable formulations of ivermectin and moxidectin respectively. A third group was used as an untreated control. Newly emerged fly larvae were reared in the dung of treated animals. Drug residues in faeces collected 3 to 35 days after treatment with an injectable formulation of moxidectin had no significant effect on the survival of larvae of M vetustissima. Similarly, faeces dropped up to seven days after treatment caused no significant reduction in larval survival in M domestica. In day 2 dung, residues of moxidectin delayed development of M vetustissima larvae, but had no effect on their survival. In contrast, ivermectin-treated steers, produced dung that inhibited larval development of both M vetustissima and M domestica for 7 to 14 days after treatment. Significant reductions in survival of M vetustissima larvae occurred in dung collected on days 21 and 28 after treatment, but by day 35 survival did not differ from t...Continue Reading

Citations

May 7, 1998·Chemosphere·B Halling-SørensenS E Jørgensen
Oct 9, 2004·Annual Review of Entomology·Kevin D FloateThomas N Sherratt
Jul 4, 2001·Environmental Toxicology and Chemistry·J DingW H Hsu
Jan 1, 2013·Ecotoxicology and Environmental Safety·Wolf U BlanckenhornJörg Römbke
Aug 28, 2003·Medical and Veterinary Entomology·R FarkasL Börzsönyi
Jan 15, 2008·Ecotoxicology and Environmental Safety·Víctor H SuárezCarlos E Lanusse
Apr 12, 2001·Medical and Veterinary Entomology·K D FloateD D Colwell

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