Effects of early vital capacity maneuver on respiratory variables during multivessel off-pump coronary artery bypass graft surgery

Critical Care Medicine
Jae Kwang ShimYoung Lan Kwak

Abstract

Despite avoiding cardiopulmonary bypass, similar degrees of pulmonary impairment compared with on-pump coronary artery bypass surgery have been demonstrated in patients undergoing off-pump coronary artery bypass graft surgery (OPCAB) compared with on-pump coronary artery bypass surgery. To investigate the effects of an early vital capacity maneuver (VCM) on intrapulmonary shunt (Qs/Qt), oxygenation, and pulmonary outcome in OPCAB. Prospective, randomized, controlled, double-blind clinical trial. Cardiothoracic operating room and intensive care unit (ICU) of a university hospital. Fifty patients scheduled for OPCAB were randomized to treatment with VCM or none. After sternotomy, VCM was performed by inflating the lungs to 40 cm H2O and holding this pressure for 10 seconds. Qs/Qt, Pao2/Fio2 (P/F) ratio, and dynamic and static pulmonary compliances were measured before induction of anesthesia (T0), 15 minutes after tracheal intubation (T1), during Y-graft construction (T2), 15 minutes after completion of grafting (T3), 15 minutes after sternal closure (T4), and 3 hours after arrival at the ICU (T5). Qs/Qt was lower and P/F ratio was higher in the VCM group at T2 through T5. Pulmonary compliances were also higher in the VCM group a...Continue Reading

References

Jan 1, 1992·Intensive Care Medicine·B Lachmann
Mar 1, 1994·Anesthesiology·T HachenbergG Hedenstierna
May 18, 1999·British Journal of Anaesthesia·G TusmanB Lachmann
Sep 3, 1999·British Journal of Anaesthesia·H U RothenG Hedenstierna
Feb 2, 2000·The Annals of Thoracic Surgery·C M CoxG D Angelini
Sep 2, 2000·The Annals of Thoracic Surgery·A P NierichJ T Knape
Feb 24, 2001·The Annals of Thoracic Surgery·M GülerC Yakut
Jun 27, 2001·Journal of Cardiothoracic and Vascular Anesthesia·G S MurphyJ S Vender
May 9, 2002·The Annals of Thoracic Surgery·Gerardo TusmanElsio Turchetto
Jul 30, 2002·Anesthesia and Analgesia·P Soeding, G Hoy
Sep 27, 2002·The Journal of Thoracic and Cardiovascular Surgery·Edda M TschernkoFranz P Keznickl
Nov 29, 2002·Anesthesia and Analgesia·A- S EichenbergerL Magnusson
Feb 19, 2004·British Journal of Anaesthesia·P-G ChassotD R Spahn
Feb 20, 2004·Journal of Cardiothoracic and Vascular Anesthesia·Philip J PeytonBruce Thompson
Apr 28, 2004·European Journal of Anaesthesiology·W OczenskiR D Fitzgerald
Jan 15, 2005·Journal of Cardiothoracic and Vascular Anesthesia·Félix R MontesFreddy Ariza
Aug 13, 2005·Intensive Care Medicine·Jonas NielsenAnders Larsson
Oct 11, 2005·Critical Care Medicine·Dinis Reis MirandaDiederik Gommers
Dec 15, 2005·Heart, Lung & Circulation·Aitizaz SyedArto Nemlander

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Citations

Jan 18, 2017·BioMed Research International·Li LiJing Yan
Oct 8, 2019·British Journal of Anaesthesia·Christopher C YoungJuraj Sprung

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