PMID: 18416086Apr 18, 2008Paper

Effects of electroacupuncture at the conception vessel on proliferation and differentiation of nerve stem cells in the inferior zone of the lateral ventricle in cerebral ischemia rats

Journal of Traditional Chinese Medicine = Chung I Tsa Chih Ying Wen Pan
Zhuoxin YangMin Pi

Abstract

To observe the effects of electroacupuncture (EA) at the Conception Vessel on proliferation and differentiation of the nerve stem cells in the inferior zone of the lateral ventricle in cerebral ischemia rats. The model rats were prepared by occlusion of the middle cerebral artery for 2 hours and then by reperfusion. They were randomly divided into two groups: a control group and an EA group. Changes in differentiation and proliferation of the nerve stem cells were observed 7, 14 and 28 days after successful modeling. As compared with the 7-day control group (C-7d group), there was no significant difference (P > 0.05) in the numbers of 5-bromodeoxyuridine (Brdu) positive cells, Brdu/GFAP, Brdu/Nestin and Brdu/Nse double-labeled cells in the inferior zone of the lateral ventricle in the EA group 7 days after modeling. However, in the 14-day EA group (R-14d group) and the 28-day EA group (R-28d group), the numbers of Brdu positive cells and Brdu/GFAP, Brdu/Nestin, Brdu/Nse double-labeled cells significantly increased as compared respectively with the 14-day control (C-14d group) and the 28-day control (C-28d) group (P < 0.05 or P < 0.01). EA at the Conception Vessel promotes differentiation and proliferation of the nerve stem cell...Continue Reading

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Citations

Jul 6, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Ming-Jing ZhaoShuo-Ren Wang
Sep 17, 2016·Progress in Biophysics and Molecular Biology·Zhimin Li, Charles Shang
Apr 12, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Jiangang LiuYan Ma
Jun 26, 2012·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Min-Wook KimManho Kim
Oct 10, 2018·Evidence-based Complementary and Alternative Medicine : ECAM·Loredana CavalliMaria Chiara Carboncini

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