Effects of Electroconvulsive Therapy on Depression and Its Potential Mechanism

Frontiers in Psychology
Ming LiRanji Cui

Abstract

Depression is one of the most common disorders causing mortality around the world. Although electroconvulsive therapy (ECT) is, along with antidepressants and psychotherapy, one of the three major treatments of depression, it is still considered as the last resort for depressed patients. This situation is partially due to limited studies and uncertainty regarding its mechanism. However, decades of increased research have focused on the effects of ECT on depression and its potential mechanism. Furthermore, these investigations may suggest that ECT should be a first-line therapy for depression due to its profound effects in relieving desperation in certain situations. Here, we outline recent clinical and preclinical studies and summarize the advantages and disadvantages of ECT. Thus, this review may provide some hints for clinical application.

References

Aug 20, 2003·The European Journal of Neuroscience·Sonia HennouMarkus U Ehrengruber
Sep 24, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Torsten M MadsenRonald S Duman
Feb 24, 2007·Genome Biology·Yoko Shiraishi-Yamaguchi, Teiichi Furuichi
Mar 3, 2010·The British Journal of Psychiatry : the Journal of Mental Science·Charles H KellnerGeorgios Petrides
Apr 22, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Patricia A ZunszainCarmine M Pariante
Jan 25, 2011·Psychosomatic Medicine·Cinnamon Stetler, Gregory E Miller
May 30, 2014·Progress in Neuro-psychopharmacology & Biological Psychiatry·C KyeremantengZ Merali
Oct 18, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Harm-Pieter SpaansRob M Kok
Nov 21, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Klaus V WagnerMathias V Schmidt
Dec 19, 2014·The International Journal of Neuropsychopharmacology·Colleen K LooIsaac Schweitzer
May 4, 2015·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Heidi Kaastrup MüllerBetina Elfving
Aug 8, 2015·Journal of Affective Disorders·Miho OtaHiroshi Kunugi
May 21, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Ping LiSu Min
Jun 9, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Filip BouckaertMathieu Vandenbulcke
Jun 22, 2016·Journal of Psychiatry & Neuroscience : JPN·Stephanie NjauKatherine L Narr
Nov 2, 2016·The American Journal of Psychiatry·Charles H KellnerUNKNOWN CORE/PRIDE Work Group
Nov 2, 2016·The American Journal of Psychiatry·Charles H KellnerUNKNOWN CORE/PRIDE Work Group
Dec 9, 2016·The Journal of ECT·Ole BrusAxel Nordenskjöld
Dec 26, 2016·Naunyn-Schmiedeberg's Archives of Pharmacology·Katarzyna SocałaPiotr Wlaź
Feb 16, 2017·European Psychiatry : the Journal of the Association of European Psychiatrists·C-S LiangW-C Chien

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Citations

Aug 25, 2020·Der Anaesthesist·T NinkeP Groene
May 29, 2020·Neuropharmacology·Matjaž StenovecRobert Zorec
May 14, 2021·Movement Disorders Clinical Practice·Pedro J Garcia Ruiz
May 18, 2021·Frontiers in Neuroscience·Nishant VermaKip A Ludwig
Oct 12, 2021·Experimental and Therapeutic Medicine·Simona TrifuMihai Bogdan Cristea

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Methods Mentioned

BETA
pharmacotherapy

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