Effects of Endurance Training Combined With Cognitive Remediation on Everyday Functioning, Symptoms, and Cognition in Multiepisode Schizophrenia Patients

Schizophrenia Bulletin
Berend MalchowP Falkai

Abstract

Aerobic exercise has been shown to improve symptoms in multiepisode schizophrenia, including cognitive impairments, but results are inconsistent. Therefore, we evaluated the effects of an enriched environment paradigm consisting of bicycle ergometer training and add-on computer-assisted cognitive remediation (CACR) training. To our knowledge, this is the first study to evaluate such an enriched environment paradigm in multiepisode schizophrenia. Twenty-two multiepisode schizophrenia patients and 22 age- and gender-matched healthy controls underwent 3 months of endurance training (30min, 3 times/wk); CACR training (30min, 2 times/wk) was added from week 6. Twenty-one additionally recruited schizophrenia patients played table soccer (known as "foosball" in the United States) over the same period and also received the same CACR training. At baseline and after 6 weeks and 3 months, we measured the Global Assessment of Functioning (GAF), Social Adjustment Scale-II (SAS-II), schizophrenia symptoms (Positive and Negative Syndrome Scale), and cognitive domains (Verbal Learning Memory Test [VLMT], Wisconsin Card Sorting Test [WCST], and Trail Making Test). After 3 months, we observed a significant improvement in GAF and in SAS-II social...Continue Reading

References

May 1, 1978·The Journal of Nervous and Mental Disease·M M WeissmanJ K Myers
Jan 1, 1987·Schizophrenia Bulletin·S R KayL A Opler
Aug 1, 1996·Psychiatric Services : a Journal of the American Psychiatric Association·P Roy-ByrneR Ries
Nov 14, 1997·Journal of Clinical Psychology·H MüllerC E Elger
Jul 23, 1998·Neuropsychology·R W Heinrichs, K K Zakzanis
Feb 2, 2000·European Archives of Psychiatry and Clinical Neuroscience·H Häfner, W an der Heiden
Jun 26, 2003·The Journal of Clinical Psychiatry·Scott W Woods
Jul 16, 2005·Issues in Mental Health Nursing·Lora Humphrey BeebeJohn Kuldau
Feb 17, 2006·Schizophrenia Bulletin·Brian KirkpatrickStephen R Marder
Dec 7, 2007·The American Journal of Psychiatry·Susan R McGurkKim T Mueser
Feb 4, 2010·Archives of General Psychiatry·Frank-Gerald PajonkPeter Falkai
May 21, 2010·Schizophrenia Bulletin·Paul Gorczynski, Guy Faulkner
Feb 22, 2011·Nordic Journal of Psychiatry·Jørn HeggelundJan Helgerud
Mar 17, 2011·The American Journal of Psychiatry·Til WykesPál Czobor
Sep 20, 2011·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Anders GustavssonUNKNOWN CDBE2010Study Group
Dec 20, 2011·Clinical Therapeutics·Christoph U CorrellJohn M Kane
Jan 13, 2012·Acta Psychiatrica Scandinavica·D VancampfortM De Hert
Jul 28, 2012·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Alkomiet HasanUNKNOWN World Federation of Societies of Biological Psychiatry (WFSBP) Task Force on Treatment Guidelines for Schizophrenia
May 7, 2013·Social Psychiatry and Psychiatric Epidemiology·H HäfnerW an der Heiden
Jul 23, 2013·European Archives of Psychiatry and Clinical Neuroscience·Berend MalchowPeter Falkai
Feb 4, 2014·European Archives of Psychiatry and Clinical Neuroscience·Viola Oertel-KnöchelFrank Hänsel
Feb 14, 2014·BMJ : British Medical Journal·Elizabeth KuipersTim Kendall
Sep 16, 2014·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Myrto T SamaraStefan Leucht

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Citations

Jul 2, 2016·Occupational Therapy International·Ming-De ChenJyh-Jong Chang
Nov 7, 2015·European Archives of Psychiatry and Clinical Neuroscience·Katriona Keller-VaradyBerend Malchow
Nov 14, 2016·Psychiatry Research·Mehala SubramaniapillaiGuy Faulkner
Mar 7, 2017·British Journal of Pharmacology·Joseph FirthAlison R Yung
Feb 24, 2017·Current Opinion in Psychiatry·Peter FalkaiAndrea Schmitt
Nov 20, 2015·Journal of the International Neuropsychological Society : JINS·Sarah C McEwenKeith H Nuechterlein
May 7, 2019·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Peter Falkai, Andrea Schmitt
Mar 25, 2015·Schizophrenia Bulletin·Iris E Sommer, René S Kahn
May 23, 2019·European Archives of Psychiatry and Clinical Neuroscience·Isabel MaurusPeter Falkai
Feb 6, 2017·European Archives of Psychiatry and Clinical Neuroscience·Andrea Schmitt, Peter Falkai
Mar 29, 2019·Frontiers in Psychiatry·Marco HerbslebBerend Malchow
Jun 1, 2017·NPJ Schizophrenia·Louise Birkedal GlenthøjMerete Nordentoft
Oct 17, 2017·Current Treatment Options in Psychiatry·Vijay A MittalStewart A Shankman
Oct 13, 2017·Frontiers in Psychiatry·Carol JahshanMichael F Green
Nov 7, 2019·Brain Imaging and Behavior·Boris-Stephan RauchmannPeter Falkai
Nov 20, 2016·Journal of Neuroscience Research·Venkanna Rao BhagyaByrathnahalli S Shankaranarayana Rao
May 1, 2020·European Psychiatry : the Journal of the Association of European Psychiatrists·Julien DubreucqUNKNOWN RemedRugby Group
Jan 21, 2021·Journal of Clinical Medicine·Sylwia KalinowskaJerzy Samochowiec
Jun 19, 2021·European Archives of Psychiatry and Clinical Neuroscience·Peter FalkaiDaniel Keeser

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