PMID: 2483823Nov 1, 1989Paper

[Effects of essentiale forte on biosynthesis of nucleic acids and several hemodynamic parameters of the damaged myocardium in rabbits].

Biulleten' eksperimental'noĭ biologii i meditsiny
K G KaragezianM A Varosian

Abstract

Normalization of heart muscle phospholipid metabolism and reactivation of the activity of membrane-bound enzymes participating in the reactions of biosynthesis of nucleic acids have been studied. These investigations were carried out under the conditions of experimental myocardial infarction. The effects of essential forte have been examined when it was combined with both a tocopherol, and sodium nucleinate. It was pointed out that essential forte using without other reagents leads to the depression of nucleic acids biosynthesis in affected heart muscle, while the combinations of it with a-tocopherol, and especially with sodium nucleinate are accompanied by the significant intensification of reactions of formation of desoxynucleic and ribonucleic acids biosynthesis in necrotic areas as well as in peripheral regions of affected myocardial tissue. These positive changes are accompanied also by the pronounced normalization of haemodynamic activity of infarcted myocardium.

References

Nov 1, 1979·Journal of Molecular and Cellular Cardiology·S C VasdevG P Biro
Jul 17, 1973·Biochemical and Biophysical Research Communications·E SantiagoJ F Segovia
Jul 1, 1972·Canadian Journal of Biochemistry·I A Menon
Jan 1, 1980·Infection·H C Spratt, M I Marks

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Citations

Dec 1, 1996·Quarterly Reviews of Biophysics·B Hartmann, R Lavery
Jan 15, 2019·Journal of Dairy Science·Nurit Argov-Argaman

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