Effects of exercise and estrogen therapy on lipid profiles of postmenopausal women

Medicine and Science in Sports and Exercise
R KlebanoffB Fernhall

Abstract

We compared the effects of aerobic exercise training on lipid and lipoprotein levels in 18 postmenopausal women who were (N = 8) or were not (N = 10) receiving estrogen replacement therapy (ERT). Each group was tested for lipids, diet recall and VO2max before and after a 12 wk exercise program, consisting of 30-50 min of an aerobic activity at 75-85% of VO2max, 3-4 sessions per week. Both groups increased VO2max by 8% and neither group changed their diet. The ERT group had higher levels of triglycerides and lower levels of low density lipoprotein (LDL-C) (P < 0.01) before training. There were no mean group changes in any of the lipid variables with training. However, individual changes in LDL-C and Total Cholesterol (TC) were strongly related to baseline weight in the nonestrogen group (r = 109.91, r = -0.82) but not in ERT (r = -0.30, r = -0.51). Subsequently, all subjects were redivided into two groups based on BMI (< or = 27 or > or = 27) regardless of ERT status. TC decreased significantly (P < 0.05) in the < or = 27 BMI group. Exercise training had little effect on the lipid profiles of the ERT and the nonestrogen groups, but body weight seems to be a modulating factor. Heavier subjects did not respond as favorably to 12 w...Continue Reading

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Citations

Jun 28, 2001·Medicine and Science in Sports and Exercise·A S Leon, O A Sanchez
Mar 16, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M ShinodaJ-M Lavoie
Oct 7, 2006·Menopause : the Journal of the North American Menopause Society·Kelley K PetteeLewis H Kuller
Mar 27, 1999·Journal of Women's Health
Jan 3, 2001·Journal of Applied Physiology·M G LatourJ M Lavoie
Aug 19, 2000·Medicine and Science in Sports and Exercise·Y HongJ P Després
Oct 7, 2004·Sports Medicine·Crystal WhitneyKarim Khan
Dec 6, 2008·Menopause : the Journal of the North American Menopause Society·Michel RousselPascale Mauriège
Aug 9, 2002·Journal of the American College of Nutrition·David C NiemanCathy C Nieman
Nov 6, 2009·Climacteric : the Journal of the International Menopause Society·A DamirchiP Babaei
Dec 9, 2008·Metabolism: Clinical and Experimental·Vitoon SaengsirisuwanChaivat Toskulkao

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