Effects of exercise training and sex on dynamic responses of O2 uptake in type 2 diabetes.

Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme
Simon GreenMikel Egaña

Abstract

Effects of training and sex on oxygen uptake dynamics during exercise in type 2 diabetes mellitus (T2DM) are not well established. We tested the hypotheses that exercise training improves the time constant of the primary phase of oxygen uptake (τp oxygen uptake) and with greater effect in males than females. Forty-one subjects with T2DM were assigned to 2 training groups (Tmale, Tfemale) and 2 control groups (Cmale, Cfemale), and were assessed before and after a 12-week intervention period. Twelve weeks of aerobic/resistance training was performed 3 times per week, 60-90 min per session. Assessments included ventilatory threshold (VT), peak oxygen uptake, τp oxygen uptake (80%VT), and dynamic responses of cardiac output, mean arterial pressure and systemic vascular conductance (80%VT). Training significantly decreased τp oxygen uptake in males by a mean of 20% (Tmale = 42.7 ± 6.2 to 34.3 ± 7.2 s) and females by a mean of 16% (Tfemale = 42.2 ± 9.3 to 35.4 ± 8.6 s); whereas τp oxygen uptake was not affected in controls (Cmale = 41.6 ± 9.8 to 42.9 ± 7.6 s; Cfemale = 40.4 ± 12.2 to 40.6 ± 13.4 s). Training increased peak oxygen uptake in both sexes (12%-13%) but did not alter systemic cardiovascular dynamics in either sex. Training...Continue Reading

References

Jun 1, 1986·Journal of Applied Physiology·W L BeaverB J Whipp
Feb 1, 1971·Journal of Applied Physiology·B J Whipp
May 1, 1995·Medicine and Science in Sports and Exercise·J G RegensteinerW R Hiatt
Mar 1, 1996·Journal of Applied Physiology·B GrassiP D Wagner
Jul 9, 1998·Journal of Applied Physiology·J G RegensteinerW R Hiatt
Aug 19, 2000·Medicine and Science in Sports and Exercise·J BalmerS R Bird
Jul 28, 2001·Exercise and Sport Sciences Reviews·R L HughsonM E Houston
Dec 8, 2004·Journal of Applied Physiology·Natasha R SaundersMichael E Tschakovsky
Apr 30, 2005·The Journal of Physiology·Stefan P MortensenJosé González-Alonso
Jun 29, 2005·Diabetes Care·Zhi You FangThomas H Marwick
Jul 18, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Danielle J PadillaDavid C Poole
Oct 4, 2006·Respiratory Physiology & Neurobiology·Danielle J PadillaDavid C Poole
Jan 9, 2007·European Journal of Applied Physiology·Mikel EgañaSimon Green
Nov 23, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·B J GurdJ M Kowalchuk
Dec 13, 2007·European Journal of Applied Physiology·Djordje G JakovljevicDavid A Brodie
Mar 5, 2008·Medicine and Science in Sports and Exercise·Sophie LalandeJames C Baldi
Apr 2, 2008·Medicine and Science in Sports and Exercise·David C PooleAndrew M Jones
Apr 7, 2009·Medicine and Science in Sports and Exercise·Judith G RegensteinerEugene E Wolfel
Nov 26, 2009·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Richard L Hughson
Nov 26, 2010·JAMA : the Journal of the American Medical Association·Timothy S ChurchConrad P Earnest
Dec 7, 2010·Medicine and Science in Sports and Exercise·Oscar Mac AnaneyMikel Egaña
Dec 24, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·D P WilkersonA C Shore
Jan 26, 2011·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Oscar MacAnaneySimon Green
Apr 15, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Juan M MuriasDonald H Paterson
Mar 17, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Gabriela De RoiaCarlo Capelli
Apr 28, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Eamonn O'ConnorMikel Egaña
May 9, 2012·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Oscar MacananeyMikel Egaña
Jul 26, 2012·European Journal of Applied Physiology·Matthew D SpencerDonald H Paterson
Apr 1, 2012·Comprehensive Physiology·David C Poole, Andrew M Jones
May 9, 2014·Medicine and Science in Sports and Exercise·Judith G RegensteinerJane E B Reusch
Apr 29, 2015·International Journal of Cardiology·Benno KrachlerRainer Rauramaa
Apr 29, 2015·Journal of Diabetes Research·Simon GreenJudith G Regensteiner
Aug 14, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Catherine KielyMikel Egaña
Dec 17, 2016·Medicine and Science in Sports and Exercise·Genevieve Abigail WilsonJames Chris Baldi
Jan 7, 2017·Cardiovascular Diabetology·Chang Hee JungUNKNOWN Taskforce Team of Diabetes Fact Sheet of the Korean Diabetes Association
Feb 6, 2017·Journal of Applied Physiology·David C Poole, Andrew M Jones
Feb 9, 2018·Journal of Applied Physiology·Veronica J PoitrasMichael E Tschakovsky
Feb 9, 2018·Journal of Applied Physiology·Simon Green, Christopher Askew

❮ Previous
Next ❯

Citations

Sep 5, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Addisu Dabi Wake
Feb 25, 2021·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Norita GildeaMikel Egaña

❮ Previous
Next ❯

Related Concepts

Related Feeds

CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.