Effects of experimental craniofacial pain on fine jaw motor control: a placebo-controlled double-blinded study

Experimental Brain Research
Abhishek KumarPeter Svensson

Abstract

The aim of the experiment was to test the hypothesis that experimental pain in the masseter muscle or temporomandibular joint (TMJ) would perturb the oral fine motor control, reflected in bigger variability of bite force values and jaw muscle activity, during repeated splitting of food morsels. Twenty healthy volunteers participated in four sessions. An intervention was made by injection of either 0.2 ml of monosodium glutamate/isotonic saline (MSG/IS) (randomized) in either the masseter or TMJ (randomized). The participants were asked to hold and split a flat-faced placebo tablet with their anterior teeth, thirty times each at baseline, during intervention and post-intervention. Pain was measured using a 0-10 visual analog scale. The force applied by the teeth to "hold" and "split" the tablet along with the corresponding electromyographic (EMG) activity of the jaw muscles and subject-based reports on perception of pain was recorded. The data analysis included a three-way analysis of variance model. The peak pain intensity was significantly higher during the painful MSG injections in the TMJ (6.1 ± 0.4) than the injections in masseter muscle (5.5 ± 0.5) (P = 0.037). Variability of hold force was significantly smaller during the...Continue Reading

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Sep 7, 2014·Archives of Oral Biology·Abhishek KumarPeter Svensson
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Citations

Aug 29, 2016·Clinical Oral Investigations·Abhishek KumarPeter Svensson
Aug 31, 2017·Journal of Oral Rehabilitation·L Avivi-Arber, B J Sessle
Jul 8, 2020·Journal of Oral Rehabilitation·Nabeel AlmotairyAnastasios Grigoriadis
Mar 6, 2019·Journal of Prosthodontic Research·Abhishek KumarMats Trulsson
Nov 2, 2016·Journal of Oral Rehabilitation·M AmhamedG M Murray
Nov 19, 2019·Frontiers in Physiology·Samaa Al SayeghNikolaos Christidis
Jul 3, 2020·Clinical Oral Investigations·Nabeel AlmotairyAnastasios Grigoriadis
Jul 30, 2017·Scientific Reports·Abhishek KumarPeter Svensson
Nov 9, 2020·Journal of Endodontics·Khaled Al-ManeiAnastasios Grigoriadis
Sep 4, 2019·Physiology & Behavior·Abhishek KumarPeter Svensson

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