Effects of exposure to the xenoestrogen octylphenol and subsequent transfer to clean water on liver and gonad ultrastructure during early development of Zoarces viviparus embryos

Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
Ase JespersenB Korsgaard

Abstract

Female eelpouts (Zoarces viviparus L.) are exposed during early pregnancy to nominal concentrations of 100 microg/L of 4-tert-octylphenol (OP) or 0.5 microg/L of 17beta-estradiol (E2). Effects on maternal metabolism and on liver and gonad development in embryos were examined and compared with controls (C) during exposure and after transfer to clean water (depuration). In the mother fish, significantly higher concentrations of plasma vitellogenin (vtg) and calcium were found in the two exposed groups, when compared with the C group after exposure and depuration. When compared, however, with the respective values after exposure, vtg had decreased significantly after depuration. The hepatosomatic index was normalized after depuration. In both exposed groups, the hepatocytes were rounded and not distinctly polygonal as in the controls. The amount of glycogen was considerably less while the number of mitochondria increased, and the rER significantly proliferated after exposure as well as after depuration. The gonads of nine of more than 28 embryos in the group treated with OP exhibited a number of abnormalities as compared with the normal gonad development in both sexes. Feminization of the male gonads in the exposed specimens and a...Continue Reading

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Aug 23, 2005·Environmental Toxicology and Chemistry·Martina FenskeHelmut Segner

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Citations

Jun 1, 2014·Environmental Science and Pollution Research International·Wen-Ling ChenChia-Yang Chen
Mar 11, 2016·Bulletin of Environmental Contamination and Toxicology·G Rey VázquezF L Lo Nostro
Feb 4, 2014·Journal of Separation Science·Hana AdamusovaVera Pacakova
Nov 8, 2014·Environmental Science & Technology·Jane E MorthorstPoul Bjerregaard

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