Effects of External Perturbations on Anticipatory and Compensatory Postural Adjustments in Patients with Multiple Sclerosis and a Fall History

International Journal of MS Care
Shirin TajaliAli E Oskouei

Abstract

Although previous studies have investigated postural adjustment mechanisms in patients with multiple sclerosis (MS), it seems that no study has yet investigated the relationship between anticipatory and compensatory postural adjustments (APAs and CPAs, respectively) and falls. Seventeen MS fallers, 17 MS nonfallers, and 15 controls were exposed to a series of expected and unexpected backward pull perturbations applied at the trunk level. The electrical activity of 12 leg and trunk muscles as well as center of pressure displacement were recorded. The MS fallers had delayed muscle activity onsets compared with MS nonfallers and controls. In addition, a significantly lower level of muscle activity during APAs was detected in MS fallers compared with controls. Moreover, in the unexpected condition of perturbation, significantly smaller CPA was observed in MS fallers compared with controls. Both groups of patients with MS required more time to stabilize their center of pressure after both types of perturbations compared with controls. The inability to produce efficient APAs and CPAs during perturbations may explain the high rates of postural instability and falls in patients with MS. Findings from this study provide a background for...Continue Reading

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Citations

Sep 22, 2020·Disability and Rehabilitation·Megan C KirklandMichelle Ploughman
Oct 18, 2018·Digestive Diseases and Sciences·Susan L MurphyJames K Richardson
Jun 9, 2020·Neurorehabilitation and Neural Repair·Mohamed Suhair Bin Mohamed SuhaimyStephen R Lord
Jan 18, 2021·Gait & Posture·Andrew S Monaghan, Daniel S Peterson
Apr 4, 2021·International Journal of Environmental Research and Public Health·Jernej SeverNejc Šarabon

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