Effects of Field-Realistic Concentrations of Carbendazim on Survival and Physiology in Forager Honey Bees (Hymenoptera: Apidae)

Journal of Insect Science
Tengfei ShiLinsheng Yu

Abstract

Carbendazim is nowadays widely used to control fungus in various nectariferous crops. Little is known about how honey bees, Apis mellifera L. (Hymenoptera: Apidae), respond to carbendazim exposure. In this study, the effects of field-realistic concentrations of carbendazim (4.516, 0.4516, and 0.04516 ppm) on the survival, biomarker enzyme activity (AChE, GST, CarE, and P450), and four antimicrobial peptide gene expression (hymenoptaecin, defensin, apidaecin, and abaecin) in forager honey bees were evaluated. The forager bees were fed with the pesticides for 10 d. The results showed that the field-realistic concentrations of carbendazim did not affect survival; activities of AChE, GST, and CarE; and expression levels of defensin and abaecin in forager bees. However, 4.516, 0.4516, and 0.04516 ppm of carbendazim all significantly inhibited the expression of hymenoptaecin and apidaecin (P < 0.01), while P450 (7-ethoxycoumarin-O-deethylase) activity was downregulated by 4.516 ppm of carbendazim (P < 0.05). Our results indicate that the field-realistic concentrations of carbendazim may alter the immune response and P450-mediated detoxification of honey bees. Thus, carbendazim should be discreetly used on nectariferous crops during f...Continue Reading

References

Apr 1, 1978·Analytical Biochemistry·A Aitio
Feb 28, 1994·Biochemical and Biophysical Research Communications·P Casteels, P Tempst
Jul 1, 1961·Biochemical Pharmacology·G L ELLMANR M FEATHER-STONE
Jan 12, 2007·Ecotoxicology and Environmental Safety·A BadiouL P Belzunces
Jun 13, 2008·Nature Protocols·Thomas D Schmittgen, Kenneth J Livak
Aug 19, 2008·The American Naturalist·Gene E Robinson
Mar 2, 2010·Trends in Ecology & Evolution·Simon G PottsWilliam E Kunin
Dec 31, 2011·Journal of Invertebrate Pathology·R R James, J Xu
Feb 10, 2012·PloS One·Reed M JohnsonMay R Berenbaum
Mar 31, 2012·Science·Mickaël HenryAxel Decourtye
Sep 22, 2012·Science·James E Cresswell, Helen M Thompson
Feb 28, 2013·Environmental Science and Pollution Research International·Monique BoilyMadeleine Chagnon
May 29, 2013·Environmental Toxicology and Chemistry·Stephan M CarvalhoAlexandra Badiou-Beneteau
Nov 16, 2013·PloS One·Marie-Pierre ChauzatMagali Ribière-Chabert
Jan 29, 2014·Microscopy Research and Technique·Aline Fernanda CataeOsmar Malaspina
Mar 19, 2016·Environmental Science & Technology·Verena ChristenKarl Fent
Apr 20, 2016·Ecotoxicology·Abdulrahim T Alkassab, Wolfgang H Kirchner
Jun 9, 2016·Environmental Science & Technology·Léa TisonRandolf Menzel
Nov 8, 2016·Ecotoxicology·Youhui Gong, Qingyun Diao
Dec 6, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zhou TongHai-Qun Cao
Jan 4, 2017·Pesticide Biochemistry and Physiology·Qiang WangQingnian Cai
Mar 2, 2017·Journal of Analytical Methods in Chemistry·Ying-Hong LiHu Zhang
Jun 24, 2017·PloS One·Alex RobinsonDavid J Spurgeon
Jul 6, 2017·The Science of the Total Environment·Pau Calatayud-VernichYolanda Picó
Oct 3, 2017·The Science of the Total Environment·Simone TosiGiovanni Guido
Mar 27, 2018·Current Biology : CB·Cristina ManjonRalf Nauen

❮ Previous
Next ❯

Citations

Sep 14, 2019·Journal of Aquatic Animal Health·Ifeanyi Christian EzeoyiliChristopher Didigwu Nwani

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.