Effects of flow-diverting device oversizing on hemodynamics alteration in cerebral aneurysms.

AJNR. American Journal of Neuroradiology
F Mut, J R Cebral

Abstract

Flow-diverting devices are increasingly being considered for large or giant aneurysms with wide necks, which are difficult to treat with coils or clips. These devices are often oversized to achieve good positioning against the artery wall. The objective of this study was to analyze the effect of oversized flow-diverting devices in altering aneurysmal flows and creating hemodynamic environments favorable for thrombosis and aneurysm occlusion. Patient-specific computational fluid dynamics models of 3 cerebral aneurysms were constructed from 3D angiography images. Numeric simulations of the hemodynamics after implanting stents of increasing diameters were performed. The corresponding modifications of hemodynamic variables such as aneurysm inflow rate, average velocity, shear rate, and wall shear stress were calculated and compared. The results indicate that because the devices are oversized, the stent cells stretch in the direction of the vessel axis, change cell angles, and result in larger cells. This change in the cell geometry causes a diminution of the hemodynamic performance of the stent. Quantitatively, stent oversizing results in larger values of aneurysm inflow rates, average velocity, shear rate, and wall shear stress co...Continue Reading

References

May 1, 1997·Annals of Biomedical Engineering·B B LieberA K Wakhloo
Apr 13, 2005·IEEE Transactions on Medical Imaging·Juan R CebralAlejandro F Frangi
Apr 13, 2005·IEEE Transactions on Medical Imaging·Juan R Cebral, Rainald Löhner
Jun 24, 2006·Journal of Magnetic Resonance Imaging : JMRI·Karl-Olof LövbladDaniel A Ruefenacht
May 8, 2008·Physiological Measurement·J R CebralN Alperin
Oct 29, 2010·Neuroradiology·Thaweesak AurboonyawatJacques Moret
Nov 16, 2010·International Journal for Numerical Methods in Biomedical Engineering·Fernando MutJuan R Cebral
Jun 7, 2011·International Journal for Numerical Methods in Biomedical Engineering·Fernando MutJuan Cebral

❮ Previous
Next ❯

Citations

Jul 12, 2012·Journal of Neurointerventional Surgery·Tim E DarsautJean Raymond
Apr 12, 2014·AJNR. American Journal of Neuroradiology·J R CebralD F Kallmes
Mar 29, 2014·AJNR. American Journal of Neuroradiology·M ShapiroP K Nelson
Aug 11, 2012·AJNR. American Journal of Neuroradiology·A MakoyevaJ Raymond
Feb 19, 2016·Medical Image Analysis·Pierre BouillotVitor Mendes Pereira
Nov 13, 2014·Journal of Neurointerventional Surgery·Simona HodisRamanathan Kadirvel
Dec 20, 2013·International Journal for Numerical Methods in Biomedical Engineering·Fernando MutJuan Cebral
Sep 17, 2013·International Journal for Numerical Methods in Biomedical Engineering·Fernando MutJuan R Cebral
Apr 11, 2014·International Journal for Numerical Methods in Biomedical Engineering·Juan R CebralDavid Kallmes
Apr 15, 2014·International Journal for Numerical Methods in Biomedical Engineering·Juan R CebralDavid Kallmes
Apr 2, 2014·International Journal for Numerical Methods in Biomedical Engineering·M RaschiJ R Cebral
Jun 13, 2015·International Journal of Computer Assisted Radiology and Surgery·Hector FernandezIgnacio Larrabide
Apr 4, 2014·Journal of Neurointerventional Surgery·Fernando MutJuan R Cebral
Feb 24, 2015·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Ignacio LarrabideDaniel A Rüfenacht
Jul 2, 2016·AJNR. American Journal of Neuroradiology·P BouillotV M Pereira
May 11, 2017·Wiley Interdisciplinary Reviews. Systems Biology and Medicine·Ali Sarrami-ForoushaniAlejandro F Frangi
Jul 4, 2018·International Journal for Numerical Methods in Biomedical Engineering·Hongtao YuBryan R Ludwig
Jan 30, 2020·Maternal & Child Nutrition·Angelina LessaCharlotte M Wright
Feb 28, 2020·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Ahmed E HusseinAli Alaraj
Jun 27, 2020·Scientific Reports·Kamil Jerzy ChodzyǹskiKarim Zouaoui Boudjeltia
Aug 29, 2018·International Journal for Numerical Methods in Biomedical Engineering·Nicolás DazeoIgnacio Larrabide
Jun 11, 2021·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Andreas SimgenUmut Yilmaz
Aug 28, 2021·AJNR. American Journal of Neuroradiology·S HadadJ R Cebral

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.