PMID: 9533119Apr 9, 1998Paper

Effects of flow types in cardiopulmonary bypass on gastric intramucosal pH

Perfusion
A HamuluO Bilkay

Abstract

The aim of this study was to determine the relationship between splanchnic perfusion and oxygen consumption, and flow types in cardiopulmonary bypass (CPB), by measuring gastric intramucosal pH. Twenty patients undergoing elective open-heart surgery were prospectively randomized to receive either pulsatile or nonpulsatile flow during CPB. Gastric intramucosal pH was measured using gastric tonometry. A flowmeter was used to measure the inferior caval vein flow. A catheter was inserted through the femoral vein to sample blood from the iliac vein. Systemic vascular resistance index, gastric intramucosal pH, inferior caval vein flow and arterial, inferior vena caval and iliac venous blood gases were recorded at different times. Gastric intramucosal pH decreased in all patients; only in the nonpulsatile group was this decrease statistically significant. After 45 min of CPB, the pH was 7.37 +/- 0.03 compared with the prebypass value of 7.48 +/- 0.04 (p = 0.00016). After weaning from CPB, the pH was 7.358 +/- 0.02 compared with the prebypass value (p = 0.000037). At 2 h post-operatively the pH was 7.416 +/- 0.025 (p = 0.02). Systemic vascular resistance index rose in all patients during bypass in both groups. These changes did not hav...Continue Reading

References

Aug 1, 1991·Critical Care Medicine·G R DoglioG Gutierrez
Oct 1, 1991·Critical Care Medicine·L LandowM P Fink
Oct 1, 1991·The Annals of Thoracic Surgery·S K OhriK M Taylor
Mar 1, 1991·The British Journal of Surgery·S P HuddyJ R Pepper
Apr 1, 1989·Archives of Surgery·W W HamptonD E Fry
Feb 1, 1986·Archives of Surgery·C J CarricoR V Maier
Oct 1, 1986·Archives of Surgery·R E WellingR S Glaser
Jun 1, 1980·The British Journal of Surgery·J Wallwork, K G Davidson
Oct 17, 1980·JAMA : the Journal of the American Medical Association·A Lucas, M H Max
May 1, 1994·The Annals of Thoracic Surgery·S K OhriK M Taylor
Feb 1, 1994·The Annals of Thoracic Surgery·J A GaerK M Taylor
May 1, 1993·The Annals of Thoracic Surgery·S K OhriK M Taylor

❮ Previous
Next ❯

Citations

Sep 7, 2005·Artificial Organs·Akira SezaiYukiyasu Sezai
Nov 30, 2000·Critical Care : the Official Journal of the Critical Care Forum·G AcklandM G Mythen
Apr 18, 2009·Anesthesia and Analgesia·Glenn S MurphyRobert C Groom
Mar 15, 2014·Interactive Cardiovascular and Thoracic Surgery·Benjamin BierbachGrischa Hoffmann
Jan 27, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Kaori TachibanaYuji Morimoto
Jun 13, 2002·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Gianfranco B FioreRoberto Fumero

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.