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Effects of food, antacid, and dosage form on the pharmacokinetics and relative bioavailability of sertindole in healthy volunteers

Biopharmaceutics & Drug Disposition

Aug 1, 1997

S L WongG. Richard Granneman

PMID: 9267685

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Abstract

The pharmacokinetic disposition and relative bioavailability of sertindole administered as a tablet dosage form under fasting conditions, in the presence of food, in the presence of antacid, and as solution was studied in a four-way crossover in young healthy male volunteers. Overall, t...read more

Mentioned in this Paper

Sertindole
Cross-Over Studies
Drug Combinations
Pharmacokinetic Aspects
Serlect
Alhydrogel
Fasting
Magnesium Hydroxide (Mg(OH)4)
Drug Kinetics
Area Under Curve
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Effects of food, antacid, and dosage form on the pharmacokinetics and relative bioavailability of sertindole in healthy volunteers

Biopharmaceutics & Drug Disposition

Aug 1, 1997

S L WongG. Richard Granneman

PMID: 9267685

DOI:

Abstract

The pharmacokinetic disposition and relative bioavailability of sertindole administered as a tablet dosage form under fasting conditions, in the presence of food, in the presence of antacid, and as solution was studied in a four-way crossover in young healthy male volunteers. Overall, t...read more

Mentioned in this Paper

Sertindole
Cross-Over Studies
Drug Combinations
Pharmacokinetic Aspects
Serlect

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