PMID: 8591007Dec 1, 1995Paper

Effects of gamma-irradiation on the survival and development of Metagonimus yokogawai metacercariae in rats

The Korean Journal of Parasitology
J Y ChaiS H Lee

Abstract

To evaluate the feasibility of irradiation as a control measure for metagonimiasis, the metacercariae of Metagonimus yokogawai were irradiated with gamma ray, either after isolation from the sweetfish (Plecoglossus altivelis) or in situ of the fish, and their survival and development in rats were observed at 7 days post-infection. The radiation dose varied from 5 to 100 Gy for the metacercaria-irradiation group and from 5 to 500 Gy for fish-irradiation group. The results showed that the worm recovery rate from the irradiation groups decreased as the radiation dose was increased. Higher doses of radiation were required for the fish-irradiation group to obtain the same results as the metacercaria-irradiation group. The LD50 of the metacercaria-irradiation group was 4.5 Gy, whereas that of the fish-irradiation group 6.2 Gy. A few number of worms which survived until 7 days in rats were severely retarded especially in the growth of their reproductive organs, i.e., complete or partial failure in the development of testes and formation of uterine eggs. The present study revealed that irradiation of sweetfish by 200 Gy is effective to control infectivity as well as development of M. yokogawai metacercaria in rats.

References

Dec 1, 1990·Kisaengch'unghak chapchi. The Korean journal of parasitology·J Y Chai, S H Lee
Sep 1, 1989·Kisaengch'unghak chapchi. The Korean journal of parasitology·S H LeeJ Y Chai
Dec 1, 1981·Kisaengch'unghak chapchi. The Korean journal of parasitology·Byong Seol SeoIn Soo Hwang

❮ Previous
Next ❯

Citations

Jul 13, 2002·Parasitology International·Jong-Yil Chai, Soon-Hyung Lee
Jan 24, 2012·Journal of Environmental Radioactivity·N J Morley
Sep 7, 2005·International Journal for Parasitology·Jong-Yil ChaiAlan J Lymbery
Jul 26, 2003·The Journal of Parasitology·J R Yu, W Y Park
Apr 2, 2003·The Korean Journal of Parasitology·Gab-Man Park, Tai-Soon Yong
Mar 18, 2009·The Korean Journal of Parasitology·Soo-Ung LeeJae-Ran Yu
Mar 1, 1996·The Korean Journal of Parasitology·J Y ChaiS H Lee
Nov 4, 2009·The Korean Journal of Parasitology·Jong-Yil ChaiHan-Jong Rim
Dec 21, 2006·Journal of Animal Science·M BerkeveldJ H M Verheijden

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.