Effects of genetic distance on heterosis in a Drosophila melanogaster model system

Genetica
Charlotte JensenTorsten N Kristensen

Abstract

Habitat fragmentation and small population sizes can lead to inbreeding and loss of genetic variation, which can potentially cause inbreeding depression and decrease the ability of populations to adapt to altered environmental conditions. One solution to these genetic problems is the implementation of genetic rescue, which re-establishes gene flow between separated populations. Similar techniques are being used in animal and plant breeding to produce superior production animals and plants. To optimize fitness benefits in genetic rescue programs and to secure high yielding domestic varieties in animal and plant breeding, knowledge on the genetic relatedness of populations being crossed is imperative. In this study, we conducted replicated crosses between isogenic Drosophila melanogaster lines from the Drosophila Genetic Reference Panel. We grouped lines in two genetic distance groups to study the effect of genetic divergence between populations on the expression of heterosis in two fitness components; starvation resistance and reproductive output. We further investigated the transgenerational effects of outcrossing by investigating the fitness consequences in both the F1- and the F3-generations. High fitness enhancements were ob...Continue Reading

References

Dec 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·M Nei
Dec 12, 2001·Heredity·W Amos, A Balmford
Mar 27, 2002·Evolution; International Journal of Organic Evolution·Amy B MarrPeter Arcese
Feb 20, 2003·Proceedings. Biological Sciences·Carles VilàHans Ellegren
Jan 22, 2004·Bioinformatics·Emmanuel ParadisKorbinian Strimmer
Dec 21, 2005·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Adefris Teklewold, Heiko C Becker
May 17, 2006·Trends in Ecology & Evolution·David A TallmonRobin S Waples
Jul 12, 2007·Proceedings. Biological Sciences·Yvonne WilliMarkus Fischer
Nov 22, 2007·Journal of Evolutionary Biology·T LeinonenJ Merilä
Oct 24, 2008·Journal of Dairy Science·P M VanRaden
Oct 12, 2010·Science·Warren E JohnsonStephen J O'Brien
Apr 14, 2011·Conservation Biology : the Journal of the Society for Conservation Biology·Richard FrankhamCharles B Fenster
Sep 20, 2011·Bioinformatics·Thibaut Jombart, Ismaïl Ahmed
Jan 20, 2012·Ecology Letters·Céline BellardFranck Courchamp
Feb 10, 2012·Nature·Trudy F C MackayRichard A Gibbs
Sep 1, 1990·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·N G EhiobuJ F Taylor
Feb 1, 1989·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·N G Ehiobu, M E Goddard
Dec 2, 2014·Trends in Ecology & Evolution·Andrew R WhiteleyDavid A Tallmon
Apr 30, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Dobril K IvanovJanet M Thornton
Aug 5, 2015·Proceedings of the National Academy of Sciences of the United States of America·Ruth A HufbauerBrett A Melbourne
Oct 17, 2016·Trends in Ecology & Evolution·Philip W Hedrick, Aurora Garcia-Dorado
May 10, 2017·Trends in Ecology & Evolution·Ary A HoffmannTorsten N Kristensen
Jun 2, 2017·Nature·Dolph Schluter, Matthew W Pennell

❮ Previous
Next ❯

Citations

Jun 13, 2019·PLoS Genetics·Michael ØrstedTorsten Nygaard Kristensen
Mar 5, 2021·Mitochondrial DNA. Part B, Resources·Dandan LiYikui Wang

❮ Previous
Next ❯

Methods Mentioned

BETA
genotyping

Software Mentioned

adegenet
R package ‘ ape
R
hierfstat
R Core Team

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.