Effects of gestational diabetes mellitus on time to delivery and pregnancy outcomes in full-term pregnancies with dinoprostone labor induction

Clinical and Experimental Hypertension : CHE
Ting-Ting JiangMei Xiao

Abstract

To investigate the effects of gestational diabetes mellitus (GDM) on time to delivery and perinatal outcomes in full-term pregnancies underwent dinoprostone-induced labor. GDM patients that underwent labor induction with dinoprostone vaginal inserts were retrospectively recruited. Full-term pregnancies with normal glucose tolerance (NGT) that underwent labor induction at the same period were recruited as control. Time to delivery and perinatal outcomes were compared between the two groups. A total of 1555 pregnancies with 226 GDM and 1329 NGT were recruited. GDM pregnancies had older ages, lower gestational age, higher body mass index (BMI) and abortion history, and more multigravida than NGT pregnancies (P< 0.05). Univariate analysis showed no significant difference in time to delivery and delivery rates between the two groups. However, after adjusted in a multivariate analysis model, the delivery rates of GDM women delivered within 12, 24, 36 or 48 h and those vaginally delivered within 12 or 36 h were significantly lower than those in the NGT group (P< 0.05). Perinatal outcomes were clinically similar between the two groups. GDM did not affect the time to delivery, cesarean delivery and other perinatal outcomes in Chinese wo...Continue Reading

References

Oct 20, 2001·American Journal of Obstetrics and Gynecology·M H IncerpiD A Wing
May 14, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Yariv YogevMoshe Hod
Oct 7, 2004·American Journal of Obstetrics and Gynecology·Hugh M EhrenbergBrian M Mercer
Mar 1, 2005·Diabetes Care·Dana DabeleaUNKNOWN Kaiser Permanente of Colorado GDM Screening Program
Oct 2, 2008·Obstetrics and Gynecology·Deborah A Wing, UNKNOWN Misoprostol Vaginal Insert Consortium
Dec 24, 2008·Obstetrics and Gynecology·Catherine Takacs WitkopWanda K Nicholson
Jul 23, 2009·Obstetrics and Gynecology·Leo PevznerDeborah A Wing
Nov 10, 2009·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Nir MelamedYariv Yogev
Oct 1, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Julia TimofeevHelain J Landy
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Apr 3, 2012·American Journal of Obstetrics and Gynecology·Melissa G RosensteinAaron B Caughey
Jan 3, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·T WongJ R Flack
Mar 13, 2014·American Journal of Obstetrics and Gynecology·Amelia L SuttonUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
Jun 10, 2014·American Journal of Obstetrics and Gynecology·Brenda NiuAaron B Caughey
Jan 27, 2017·Journal of Perinatology : Official Journal of the California Perinatal Association·J S HawkinsD A Wing

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Citations

Dec 3, 2021·American Journal of Perinatology·Jennifer Y DuffyDeborah A Wing

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