Effects of green tea consumption on glycemic control: a systematic review and meta-analysis of randomized controlled trials

Nutrition & Metabolism
Renfan XuGuangzhi Chen

Abstract

The results of human clinical trials investigating the effects of green tea on glycemic control are inconsistent. We conducted a systematic review and meta-analysis of RCTs that examined the effects of green tea supplementation on glycemic control. A literature search in PubMed, Embase, and Cochrane Library databases for RCTs that investigated the effect of green tea consumption on glycemic control was performed up to February 2020. A random-effects model was used to estimate weighted mean difference (WMD) with 95% confidence intervals (CIs). Twenty-seven trials involving 2194 subjects were included in the meta-analysis. The pooled results showed that green tea significantly lowered fasting blood glucose by - 1.44 mg/dL (95%CI:-2.26, - 0.62 mg/dL; P < 0.001) with no obvious heterogeneity (I2 = 7.7%). However, green tea consumption did not significantly affect fasting insulin and HbA1c values. The mean differences were - 0.46μIU/mL (95% CI: - 1.10, 0.17μIU/mL; P = 0.21) for fasting insulin and - 0.06%; (95% CI: - 0.12, 0.01%; P = 0.07) for HbA1c concentrations. Heterogeneity was significant in fasting insulin (I2 = 46.8%) and mild in HbA1c (I2 = 1.7%). In short-term trials, green tea supplementation significantly reduced fasting...Continue Reading

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Citations

Jan 15, 2021·The Journal of Experimental Biology·Ayaka ItohMinoru Saito
Mar 7, 2021·Nutrients·Annalisa NoceNicola Di Daniele
May 13, 2021·Food & Function·Daniel Hinojosa-NogueiraJosé Ángel Rufián-Henares
Aug 17, 2021·Annals of Medicine·Abby Keller, Taylor C Wallace

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