Effects of GSM-modulated radiofrequency electromagnetic fields on mouse bone marrow cells

Radiation Research
Maria Grazia PriscoC Pioli

Abstract

We examined the effects of in vivo exposure to a GSM-modulated 900 MHz RF field on the ability of bone marrow cells to differentiate, colonize lymphatic organs, and rescue lethally X-irradiated mice from death. X-irradiated mice were injected with medium alone or containing bone marrow cells from either RF-field-exposed (SAR 2 W/kg, 2 h/day, 5 days/ week, 4 weeks) or sham-exposed or cage control donor mice. Whereas all mice injected with medium alone died, mice that received bone marrow cells survived. Three and 6 weeks after bone marrow cell transplantation, no differences in thymus cellularity and in the frequencies of differentiating cell subpopulations (identified by CD4/CD8 expression) were observed among the three transplanted groups. Mitogen-induced thymocyte proliferation yielded comparable levels in all transplanted groups. As to the spleen, no effects of the RF-field exposure on cell number, percentages of B and T (CD4 and CD8) cells, B- and T-cell proliferation, and IFN-gamma production were found in transplanted mice. In conclusion, our results show no effect of in vivo exposure to GSM-modulated RF fields on the ability of bone marrow precursor cells to home and colonize lymphoid organs and differentiate in phenotyp...Continue Reading

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Citations

Sep 13, 2011·Progress in Biophysics and Molecular Biology·Manolo SambucciClaudio Pioli
May 9, 2015·International Journal of Radiation Biology·Gaurav KumarAndrew W Wood
Apr 4, 2015·Journal of Radiation Research·Shin OhtaniKazuyuki Ishii
Sep 22, 2020·Expert Review of Hematology·Mina DarvishiAbbas Khosravi

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Computer Simulation Technology Microwave Studio
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