PMID: 108943Dec 1, 1978

Effects of haemoglobin electrophoretic pattern and seasonal changes on urine concentration in young adult Nigerian males

African Journal of Medicine and Medical Sciences
G O TaylorI Saliu


Renal concentrating capacity has been measured in healthy young adult Nigerian males with normal (AA) and abnormal (AS) haemoglobin types in both the dry and the wet seasons after 13 to 15 hours hydropenia respectively. The results show that, in the dry season, urine osmolality values in AA subjects are similar to those observed in Caucasians. They further confirm that renal concentrating capacity is impaired in persons with the S gene, and emphasize the limitations of the specific gravity test as a measure of renal concentrating capacity. In healthy AA subjects, the urine osmolality during the wet season is significantly less than in the dry season, even after longer periods of hydropenia. AS subjects, on the other hand, exhibit no seasonal variation in renal concentrating capacity.

Related Concepts

Hemoglobin A
Hemoglobin SS
Kidney Concentrating Ability
Seasonal Variation

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.

Related Papers

African Journal of Medicine and Medical Sciences
C H Anyanwu, B U Umeh
Proceedings of the Society for Experimental Biology and Medicine
J H Gans
Nigerian Journal of Medicine : Journal of the National Association of Resident Doctors of Nigeria
O M Atalabi
Transactions of the Royal Society of Tropical Medicine and Hygiene
G O OkaforW C Marshall
© 2021 Meta ULC. All rights reserved