PMID: 6978301Dec 1, 1981Paper

Effects of heavy ions on rabbit tissues: alopecia

International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine
A B CoxJ T Lett

Abstract

During extended investigations of the radiation responses of optic and proximate tissues of New Zealand white rabbits (Oryctolagus cuniculus), the skin surrounding the eyes was exposed to the Bragg plateau regions of 530 MeV/amu Ar ions and 365 MeV/amu Ne ions, and also to 60Co gamma rays. The linear energy transfers (LET infinity s) for the radiations were 90 +/- 5, 35 +/- 3, and 0.3 keV/micron, respectively. Alopecia was measured after irradiation with subjective indices of baldness (0-5) that were calibrated against hair loss in other rabbits irradiated with Ne and Ar ions at the central region of the ear. The patterns of post-irradiation alopecia, which conformed to the model proposed by Casarett (1963) for the long-term expression of radiation damage in proliferating animal tissues, were modified by radiation quality in the following ways: (1) For acute (early) losses, the magnitude of the recovery phase decreased as the LET infinity of the incident radiation increased; (2) In the intermediate or plateau phase of radiation response, the values of relative biological effectiveness (r.b.e) approached those reported for proliferating cells in culture, but differences were found that may be related to the changes in the magnit...Continue Reading

References

Jan 1, 1977·International Journal of Radiation Oncology, Biology, Physics·H D SuitE Gragoudas
Sep 1, 1978·International Journal of Dermatology·F D Malkinson, J T Keane
Mar 5, 1979·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·M Antal
Aug 1, 1979·International Journal of Radiation Oncology, Biology, Physics·M L GriemR M Lee
Dec 31, 1980·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·H NagasawaJ T Lett
Jan 1, 1980·Life Sciences and Space Research·J T LettD S Bergtold
Jul 1, 1952·The American Journal of Anatomy·J R GEARY
Sep 1, 1957·The Journal of Investigative Dermatology·E J VAN SCOTT, R P REINERTSON

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Citations

Feb 1, 1982·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·P C KengJ T Lett

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