Effects of heavy maternal smoking on intrauterine growth patterns in sudden infant death victims and surviving infants

European Journal of Pediatrics
J SchellscheidtJ Menke

Abstract

Sudden infant death (SID) is associated with both intrauterine growth retardation and maternal smoking during pregnancy. Here, we investigated if the statistical association between maternal smoking and SID is direct or mediated through the well-known growth retarding effects of heavy maternal smoking on the fetoplacental unit. We analysed data from a population-based prospective cohort study (181 cases, total newborn population 227,791 births) within the Westphalian Perinatal Inquiry in Germany between 1990 and 1994. SID victims whose mothers did not smoke had a normal mean birth weight (mean 3415.5 vs 3431.5 g), length (mean 51.46 vs 51.66 cm), and body mass index (BMI) (mean 12.8 vs 12.8 kg/m2) when compared to surviving children. In contrast, SID victims of mothers who smoked heavily (> ten cigarettes per day) had a significantly lower birth weight (2911.21 g vs 3148.34 g), length (48.98 vs 50.39 cm), and BMI (11.8 vs 12.4 kg/m2) when compared to surviving children whose mothers smoked heavily. Stratification for gestational age revealed that these differences are mainly caused by preterm SID infants. The statistical association between maternal smoking and SID mainly results from effects of tobacco smoke on the fetoplacent...Continue Reading

Citations

Feb 24, 2001·Acta Obstetricia Et Gynecologica Scandinavica·I WinboB Källén
Aug 22, 2000·Archives of Disease in Childhood·K WisborgN J Secher
Jun 15, 2010·European Journal of Pediatrics·Alain BraillonGérard Dubois
Oct 8, 2009·Acta Paediatrica·Edwin A Mitchell
Apr 1, 2008·Acta Paediatrica·E A MitchellM M T Vennemann
Jul 27, 2007·Journal of Forensic and Legal Medicine·Yasemin BalciCoşkun Yirulmaz
Jan 11, 2007·Sleep Medicine Reviews·A J GunnE A Mitchell
Apr 6, 2017·The Cochrane Database of Systematic Reviews·Kim PsailaHeather E Jeffery
Sep 8, 2005·American Journal of Physiology. Endocrinology and Metabolism·Kaiping YangHaiyan Guan
Oct 12, 2012·Journal of Nursing Management·Judith A Westphal
Feb 14, 2021·BMC Pregnancy and Childbirth·Veronika GüntherManfred Voigt
Jan 22, 2005·Birth Defects Research. Part C, Embryo Today : Reviews·Mary Frances McAleer, Rocky S Tuan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.