Effects of heterozygosity on performance of purebred and crossbred pigs

Genetics, Selection, Evolution : GSE
M W IversenT H E Meuwissen

Abstract

In pigs, crossbreeding aims at exploiting heterosis, but heterosis is difficult to quantify. Heterozygosity at genetic markers is easier to measure and could potentially be used as an indicator of heterosis. The objective of this study was to investigate the effect of heterozygosity on various maternal and production traits in purebred and crossbred pigs. The proportion of heterozygosity at genetic markers across the genome for each individual was included in the prediction model as a fixed regression across or within breeds. Estimates of regression coefficients of heterozygosity showed large effects for some traits. For maternal traits, regression coefficient estimates were always in a favourable direction, while for production, meat and slaughter quality traits, they were both favourable and unfavourable. Traits with the largest estimated effects of heterozygosity were total number born, litter weight at 3 weeks, weight at 150 days, and age at 40 kg. Estimates of regression coefficients on heterozygosity differed between breeds. Traits with the largest effect of heterozygosity also showed a significant (P < 0.05) increase in prediction accuracy when heterozygosity was included in the model compared to the model without hetero...Continue Reading

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Citations

Jun 20, 2020·G3 : Genes - Genomes - Genetics·David González-DiéguezZulma G Vitezica
Jul 3, 2020·Genetics, Selection, Evolution : GSE·Øyvind Nordbø
Apr 6, 2021·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Robert W A PottsRoss D Houston
Apr 28, 2021·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Seema YadavKai P Voss-Fels

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Methods Mentioned

BETA
chips
chip
genotyping

Software Mentioned

SNP
Alphaimpute
MiXBLUP
ssGBLUP
GBLUP
Fimpute

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