Effects of high alpha-linolenate and linoleate diets on erythrocyte deformability and hematological indices in rats

Lipids
K SakaiR C Reitz

Abstract

Rats were fed either a high alpha-linolenate diet or a high linoleate diet from weaning to 4 mon of age. Soybean oil was used as a control. Phospholipid compositions of erythrocytes from the three dietary groups were not significantly different. However, the difference in the alpha-linolenate (18:3n-3)/linoleate (18:2n-6) ratio of the diets was reflected in the n-3/n-6 ratios of the 20 and 22 carbon highly unsaturated fatty acids except for docosahexaenoic acid (22:6n-3) in the phospholipids. Despite the significant differences in the fatty acid compositions of phospholipids, no measurable differences were detectable in erythrocyte deformability, whole blood viscosity and hematological indices of the three dietary groups. These results indicate that the beneficial effects of the high alpha-linolenate diet, as compared with the high linoleate diet, are exerted without significant changes in these parameters.

References

Jan 21, 1978·Lancet·J Dyerberg, H O Bang
Nov 1, 1979·Prostaglandins and Medicine·B R CulpW E Lands
Feb 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·P NeedlemanH Sprecher
Jan 1, 1976·Acta Medica Scandinavica·H O BangN Hjøorne
Sep 1, 1987·Chemical & Pharmaceutical Bulletin·T HoriK Kojima
Aug 1, 1987·Environmental Health Perspectives·N MaedaT Shiga
May 1, 1986·Scandinavian Journal of Clinical and Laboratory Investigation·C Popp-SnijdersE A van der Veen
Aug 21, 1986·Biochimica Et Biophysica Acta·H G ParsonsA Kuksis
Dec 1, 1986·Biochimica Et Biophysica Acta·J MurakamiT Shiga
Apr 11, 1985·Biochimica Et Biophysica Acta·T ShigaM Okazaki
May 9, 1985·The New England Journal of Medicine·D KromhoutC de Lezenne Coulander
Jun 9, 1970·Biochimica Et Biophysica Acta·B AkessonG Arvidson
May 1, 1969·Journal of Applied Physiology·H Schmid-SchoenbeinR Schildkraut
Jul 25, 1981·Lancet·S KobayashiA Kumagai
Feb 25, 1984·British Medical Journal·B E WoodcockF E Preston
Jul 1, 1983·Thrombosis Research·A HiraiA Kumagai
Mar 1, 1982·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·S H GoodnightD R Illingworth
Mar 1, 1980·The American Journal of Clinical Nutrition·D H Hwang, A E Carroll
Dec 1, 1980·The American Journal of Clinical Nutrition·H O BangH M Sinclair

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Citations

Jan 1, 1991·Progress in Lipid Research·S M Innis
Dec 3, 2014·Biotechnology Advances·Stamatia BellouGeorge Aggelis
Jun 25, 1998·Japanese Journal of Pharmacology·S YoshidaH Okuyama
Nov 1, 2018·Comprehensive Reviews in Food Science and Food Safety·Bhakti Tanna, Avinash Mishra

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