Effects of hormone therapy on ambulatory blood pressure in postmenopausal Korean women

Climacteric : the Journal of the International Menopause Society
D-Y LeeB-K Yoon

Abstract

Previous studies of the effects of postmenopausal hormone therapy (HT) on blood pressure have yielded inconsistent results. To examine the impact of HT on 24-h ambulatory blood pressure. A total of 67 postmenopausal Korean women (age 57.1 ± 5.7 years) received 2 months of HT consisting of conjugated equine estrogen (CEE, 0.625 mg/day) with or without micronized progesterone (100 mg/day). Ambulatory blood pressure monitoring was performed at baseline and after HT. Subjects were divided into those with normal blood pressure (n = 25) and those with high blood pressure (n = 42), based on their baseline daytime blood pressure. Parity and body mass index were higher in the group with high blood pressure than in the group with normal blood pressure. For both systolic and diastolic blood pressures throughout the day, significant negative correlations were observed between basal blood pressure and blood pressure difference after HT. During the daytime period, HT increased systolic and diastolic blood pressures in the subjects with normal blood pressure and decreased systolic and diastolic blood pressures in those with high blood pressure. When micronized progesterone was added to the CEE treatment, the increase in daytime blood pressure...Continue Reading

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Citations

Apr 23, 2013·Drugs·Shelley Elkinson, Lily P H Yang
Jun 20, 2013·Menopause : the Journal of the North American Menopause Society·Joann V Pinkerton, Frank Z Stanczyk
Dec 2, 2014·International Journal of Hypertension·Shu C ChenHsien W Kuo
Jul 17, 2013·Climacteric : the Journal of the International Menopause Society·M L'Hermite
Mar 28, 2012·Climacteric : the Journal of the International Menopause Society·A O Mueck
Oct 1, 2014·Menopause : the Journal of the North American Menopause Society·Zeinab IssaGhada El-Hajj Fuleihan
Aug 16, 2013·Reproductive Sciences·Sarah L Berga
Jan 9, 2014·Menopause : the Journal of the North American Menopause Society·James A Simon
Sep 11, 2019·Medicina·Paola VillaGiovanni Scambia
May 10, 2012·FEMS Microbiology Letters·Enikő Sajben-NagyLászló Manczinger
Oct 24, 2018·Current Atherosclerosis Reports·Carson Keck, Marian Taylor

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