Effects of hyperbaric oxygen treatment on auditory hair cells after acute noise damage.

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Gleice Cristina ColombariMiguel Angelo Hyppolito

Abstract

Acute acoustic trauma (AAT) is a sudden sensorineural hearing loss caused by exposure of the hearing organ to acoustic overstimulation, typically an intense sound impulse, hyperbaric oxygen therapy (HOT), which favors repair of the microcirculation, can be potentially used to treat it. Hence, this study aimed to assess the effects of HOT on guinea pigs exposed to acoustic trauma. Fifteen guinea pigs were exposed to noise in the 4-kHz range with intensity of 110 dB sound level pressure for 72 h. They were assessed by brainstem auditory evoked potential (BAEP) and by distortion product otoacoustic emission (DPOAE) before and after exposure and after HOT at 2.0 absolute atmospheres for 1 h. The cochleae were then analyzed using scanning electron microscopy (SEM). There was a statistically significant difference in the signal-to-noise ratio of the DPOAE amplitudes for the 1- to 4-kHz frequencies and the SEM findings revealed damaged outer hair cells (OHC) after exposure to noise, with recovery after HOT (p = 0.0159), which did not occur on thresholds and amplitudes to BAEP (p = 0.1593). The electrophysiological BAEP data did not demonstrate effectiveness of HOT against AAT damage. However, there was improvement of the anatomical pa...Continue Reading

References

Jan 1, 1992·Advances in Experimental Medicine and Biology·D J Bakker
Jan 1, 1988·Progress in Neurobiology·N A Shaw
Sep 1, 1985·The Journal of the Acoustical Society of America·J C SaundersM E Schneider
Nov 1, 1995·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·G E Hyde, E W Rubel
Jan 1, 1996·Auris, Nasus, Larynx·O OzturanG R Lynch
Jun 1, 1997·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·K C Sie, S J Norton
Aug 1, 1997·Hearing Research·N HarelR V Harrison
May 20, 1998·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·G C AllenM K Wax
Dec 2, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·B D RessB L Lonsbury-Martin
Jun 8, 2000·Annals of the New York Academy of Sciences·K Lamm, W Arnold
Jun 8, 2000·Annals of the New York Academy of Sciences·C d'AldinA Dancer
Jul 26, 2000·Acta Oto-laryngologica. Supplementum·J KuokkanenJ Ylikoski
Oct 5, 2001·Acta Oto-laryngologica·J JeroA K Lalwani
Jan 15, 2005·Free Radical Biology & Medicine·Tsuyoshi EndoJuichi Ito
Jun 23, 2006·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Burak Omür CakirSuat Turgut
Jul 9, 2008·Acta Oto-laryngologica·J YlikoskiS Savolainen
Jun 1, 1997·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Kathleen C Y Sie, Susan J Norton

❮ Previous
Next ❯

Citations

Oct 12, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Alex StroseJosé Antônio Aparecido de Oliveira
Jun 8, 2013·Brazilian Journal of Otorhinolaryngology·Luciana de Albuquerque Salviano AmoraDjalma José Fagundes
May 22, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·A B Bayoumy, J A de Ru
Oct 22, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Mahmut OgurluEngin Dursun
Sep 26, 2012·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Hasan Hüseyin ArslanEmine Yilmaz
May 1, 2021·International Journal of Environmental Research and Public Health·Richard HolyJaromir Astl

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.