PMID: 9178854May 9, 1997Paper

Effects of hypothermia on the neuronal activity, [Ca2+]i accumulation and ATP levels during oxygen and/or glucose deprivation in hippocampal slices of guinea pigs

Neuroscience Letters
T TakataY Okada

Abstract

The protective effects of mild hypothermia (33 and 29 degrees C) on the neuronal activity, intracellular Ca2+ accumulation and ATP levels during deprivation of oxygen and/or glucose were investigated using guinea pig hippocampal slices. During oxygen and glucose deprivation and oxygen deprivation only, mild hypothermia had only minor effects on the maintenance of neuronal activity and ATP levels, but it suppressed Ca2+ accumulation and drastically improved the reversibility of neuronal activity. During glucose deprivation only, mild hypothermia could maintain the neuronal activity as well as ATP levels.

References

Jan 1, 1992·Acta Neuropathologica·C D AgardhB K Siesjö
Jul 1, 1989·Stroke; a Journal of Cerebral Circulation·R BustoM D Ginsberg
Dec 1, 1987·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·R BustoM D Ginsberg

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Citations

Mar 4, 2008·Journal of Physiology and Biochemistry·J JordánT Segura
Jan 29, 2005·Current Treatment Options in Neurology·D Georgiadis, Stefan Schwab
Feb 24, 2009·Journal of Neurotrauma·Thomas M Hemmen, Patrick D Lyden
Nov 21, 2012·Medical Devices : Evidence and Research·Qingwei LiuHongyu An
Dec 11, 2013·Translational Stroke Research·K KucharzH Toresson
Sep 5, 2008·Journal of the Neurological Sciences·Seung-Hoon LeeByung-Woo Yoon
Nov 21, 2007·Journal of the Neurological Sciences·Arturo JaramilloVioleta Díaz
Apr 22, 2008·Expert Opinion on Pharmacotherapy·Tomás SeguraJoaquin Jordan
Oct 18, 2002·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Valery L FeiginAlistair J Gunn
Aug 19, 2008·International Journal of Stroke : Official Journal of the International Stroke Society·Patrick D LydenW Dalton Dietrich
Oct 11, 2017·Pediatric Research·Makoto NabetaniTakashi Hamazaki
Jan 31, 2007·Stroke; a Journal of Cerebral Circulation·Thomas M Hemmen, Patrick D Lyden
Nov 22, 2018·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Patrick D LydenPadmesh S Rajput

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