Effects of Hypothermic Cardiopulmonary Bypass on Internal Jugular Bulb Venous Oxygen Saturation, Cerebral Oxygen Saturation, and Bispectral Index in Pediatric Patients Undergoing Cardiac Surgery: A Prospective Study

Medicine
Zhiyong HuPatrick M McQuillan

Abstract

The objective of this study was to evaluate the effect of hypothermic cardiopulmonary bypass (CPB) on cerebral oxygen saturation (rSO2), internal jugular bulb venous oxygen saturation (SjvO2), mixed venous oxygen saturation (SvO2), and bispectral index (BIS) used to monitor cerebral oxygen balance in pediatric patients.Sixty American Society of Anesthesiologists Class II-III patients aged 1 to 4 years old with congenital heart disease scheduled for elective cardiac surgery were included in this study. Temperature, BIS, rSO2, mean arterial pressure, central venous pressure, cerebral perfusion pressure (CPP), and hematocrit were recorded. Internal jugular bulb venous oxygen saturation and SvO2 were obtained from blood gas analysis at the time points: after induction of anesthesia (T0), beginning of CPB (T1), ascending aortic occlusion (T2), 20 minutes after initiating CPB (T3), coronary reperfusion (T4), separation from CPB (T5), and at the end of operation (T6). The effect of hypothermia or changes in CPP on rSO2, SjvO2, SvO2, and BIS were analyzed.Compared with postinduction baseline values, rSO2 significantly decreased at all-time points: onset of extracorporeal circulation, ascending aortic occlusion, 20 minutes after CPB ini...Continue Reading

References

Jun 29, 2005·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jeffrey Alten, M Michele Mariscalco
Jan 20, 2012·Advances in Experimental Medicine and Biology·J AshmoreM Thorniley
Dec 4, 2013·Journal of Cardiothoracic and Vascular Anesthesia·Caetano Nigro NetoMaria Angela Tardelli
Mar 1, 2014·Frontiers in Physiology·Lars NyboNiels H Secher
May 16, 2014·British Journal of Anaesthesia·A E Schwartz
May 21, 2014·Saudi Journal of Anaesthesia·Mohmaed Shaaban AliMohamed Gomaa Almaz

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Citations

Feb 11, 2018·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Andres Zorrilla-VacaMarek A Mirski
May 10, 2018·Therapeutic Hypothermia and Temperature Management·Michelle HillLeslie A Hamilton
May 29, 2018·Case Reports in Critical Care·J Scott Baird
Apr 11, 2019·The Journal of International Medical Research·Jin GongXiaobing Li

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Methods Mentioned

BETA
sedation

Software Mentioned

SPSS

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